APC-H-2Kb/Human MAGE-A5 (HNTQYCNL) MHC Tetramer (CAT#: MHC-LC215)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MAGE-A5-derived peptide of HNTQYCNL sequence covering 5-12 and H-2Kb molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- H-2Kb
- Class
- Class I
- Antigen
- MAGE-A5
- Antigen Species
- Human
- Peptide
- HNTQYCNL
- Range
- 5-12
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene.
- Alternative Names
- MAGEA5; MAGE family member A5; CT1.5; MAGE5; MAGEA4
- Gene ID
- 4104
- UniProt ID
- P43359
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MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC214 | PE-H-2Kb/Human MAGE-A5 (HNTQYCNL) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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