APC-H-2Kd/Human Islet-specific glucose-6-phosphatase catalytic subunit related protein (VYLKTNVFL) MHC Tetramer (CAT#: MHC-LC695)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Islet-specific glucose-6-phosphatase catalytic subunit related protein-derived peptide of VYLKTNVFL sequence covering 206-214 and H-2Kd molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
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Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • Antigen
  • Islet-specific glucose-6-phosphatase catalytic subunit related protein
  • Antigen Species
  • Human
  • Peptide
  • VYLKTNVFL
  • Range
  • 206-214
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined.
  • Alternative Names
  • G6PC2; glucose-6-phosphatase catalytic subunit 2; IGRP

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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