I-Ab/Friend murine leukemia virus envelope protein (EPLTSLTPRCNTAWNRLKL) MHC Tetramer (CAT#: MHC-LC222)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Friend murine leukemia virus envelope protein-derived peptide of EPLTSLTPRCNTAWNRLKL sequence covering 123-141 and I-Ab molecule. The pMHC tetramer recognizes human CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

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Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

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Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • I-Ab
  • Class
  • Class II
  • MHC Species
  • Mouse
  • Antigen
  • Friend murine leukemia virus envelope protein
  • Antigen Species
  • FMLV
  • Peptide
  • EPLTSLTPRCNTAWNRLKL
  • Range
  • 123-141
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The Friend virus (FV) is a strain of murine leukemia virus identified by Charlotte Friend in 1957. The virus infects adult immunocompetent mice and is a well-established model for studying genetic resistance to infection by an immunosuppressive retrovirus. The Friend virus has been used for both immunotherapy and vaccines. It is a member of the retroviridae group of viruses, with its nucleic acid being ssRNA.
  • Alternative Names
  • FMLV env; Friend murine leukemia virus envelope protein envelope protein

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