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Imiglucerase (CAT#: TP-015CL)

Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues


See more Therapeutic Protein products for GBA
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
Figure 1 IHC staining of human prostate
Figure 1 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong granular cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37171/ihc_selected.jpg
Figure 2 Liver
Figure 2 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37289/84609_A_9_4.jpg
Figure 3 Kidney
Figure 3 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37289/84609_A_7_5.jpg
Figure 4 Testis
Figure 4 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37289/84609_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177628-GBA

Specifications

  • Classify
  • Protein therapeutics replacing a protein that is deficient or abnormal: Metabolic enzyme deficiencies
  • Therapeutic
  • β-Gluco-cerebrosidase
  • Trade Name
  • Cerezyme
  • Function
  • Hydrolyzes glucocerebroside to glucose and ceramide
  • Examples of clinical use
  • Gaucher's disease

References

  • Synonyms
  • Not Available
  • UniProt
  • P04062
  • Genbank
  • M16328

Downloads

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See other products for "GBA"

Recombinant Antibody

CAT Product Name Application Type
MOB-1694z Mouse Anti-GBA Recombinant Antibody (clone 22G4) WB, IHC Mouse IgG2a
MOB-1992MZ Recombinant Mouse Anti-Human GBA Antibody (clone 2E2) ICC/IF, IHC-Fr, IHC-P, WB Mouse antibody
MRO-0639-CN Rabbit Anti-GBA Recombinant Antibody (clone JM10-76) WB, IHC Rabbit IgG
ZG-0682J Rabbit Anti-GBA Recombinant Antibody (clone 4H4) ELISA, WB Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1408 Hi-Affi™ Rabbit Anti-GBA Recombinant Antibody (clone DS1408AB) WB, IHC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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