Insulin Human (CAT#: TP-002CL)

Insulin human is a 51 residue peptide hormone, composed of two amino acid chains covalently linked by disulfide bonds. The structure is identical to native human insulin. Recombinant insulin is synthesized by recombinant DNA techncology. Inserting the human insulin gene into the Escherichia coli bacteria or Saccharomyces cerevisiae produces insulin for human use.

Inhalable insulin is a powdered form of insulin regular, delivered with a nebulizer into the lungs where it is absorbed. Exubera, developed by Inhale Therapeutics (later named Nektar Therapeutics), became the first inhaled insulin product to be marketed in 2006 by Pfizer, but poor sales led Pfizer to withdraw it in 2007. Afrezza, a monomeric inhaled insulin developed by Mannkind, was approved by the FDA in 2014.


  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Classify
  • Protein therapeutics replacing a protein that is deficient or abnormal: Endocrine disorders (hormone deficiencies)
  • Therapeutic
  • Insulin human inhalation
  • Trade Name
  • Exubera
  • Function
  • Insulin formulated for inhalation with faster onset of action
  • Examples of clinical use
  • Diabetes mellitus

References

  • Synonyms
  • Inhaled insulin, Insulin (human), Insulin human, Insulin human [rDNA origin], Insulin Human Regular, Insulin Recombinant Human, Insulin Recombinant Purified Human, Insulin regular, Regular Insulin, human
  • UniProt
  • Q8HXV2
  • Genbank
  • AY137503

Related Resources

  • Related Diseases

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "INS"

Single-domain Antibody

CAT Product Name Application Type
NAB-1554-VHH Recombinant Anti-human INS VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1841 Rabbit Anti-INS Recombinant Antibody (clone DS1841AB) IHC-P, WB Rabbit IgG
MOR-4627 Rabbit Anti-INS Recombinant Antibody (clone TH140DS) IF, ICC, IHC Rabbit IgG

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