Lepirudin (CAT#: TP-074CL)
Lepirudin is identical to natural hirudin except for substitution of leucine for isoleucine at the N-terminal end of the molecule and the absence of a sulfate group on the tyrosine at position 63. It is produced via yeast cells. Bayer ceased the production of lepirudin (Refludan) effective May 31, 2012.
Specifications
- Classify
- Protein therapeutics providing a novel function or activity: Haemostasis and thrombosis
- Therapeutic
- Lepirudin
- Trade Name
- Refludan
- Function
- Recombinant hirudin, a thrombin inhibitor from the salivary gland of the medicinal leech Hirudo medicinalis
- Examples of clinical use
- Heparin-induced thrombocytopaenia
References
- Synonyms
- Hirudin variant-1, Lepirudin recombinant
- UniProt
- P01050
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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