PE-A*01:01/Human CFH (CSDDGFWSK) MHC Tetramer (CAT#: MHC-LC4399)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CFH of peptide CSDDGFWSK covering 192-200 and A*01:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong plasma positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49176/ihc_selected.jpg
(Immunohistochemical staining of human small intestine shows strong plasma positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49176/ihc_selected.jpg
Figure 2 IHC staining of human ovary
(Immunohistochemical staining of human ovary shows distinct positivity in plasma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53326/ihc_selected.jpg
(Immunohistochemical staining of human ovary shows distinct positivity in plasma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53326/ihc_selected.jpg
Figure 3 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows distinct positivity in plasma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/ihc_selected.jpg
(Immunohistochemical staining of human duodenum shows distinct positivity in plasma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/ihc_selected.jpg
Figure 4 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/37049_A_8_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/37049_A_8_3.jpg
Figure 5 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/37049_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/37049_A_9_5.jpg
Figure 6 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/37049_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16385/37049_A_6_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (HHSteC, HSkMC, hTERT-RPE1, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000000971-CFH
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000000971-CFH
Specifications
- Allele
- A*01:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- CFH
- Antigen Species
- Human
- Peptide
- CSDDGFWSK
- Range
- 192-200
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]
- Alternative Names
- CFH; Complement factor H; FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3
- Gene ID
- 3075
- UniProt ID
- P08603
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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