APC-A*02:01/Human DCT (VVMGTLVAL) MHC Tetramer (CAT#: MHC-LC2938)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human DCT of peptide VVMGTLVAL covering 475-483 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10742/1844_A3_33_selected.jpg

(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10743/ihc_selected.jpg

(Melanocytes Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10743/26206_B_9_1.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000080166-DCT
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- DCT
- Antigen Species
- Human
- Peptide
- VVMGTLVAL
- Range
- 475-483
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. Its expression is regulated by the microphthalmia-associated transcription factor (MITF).
- Alternative Names
- DCT; dopachrome tautomerase; TRP-2; TYRP2
- Gene ID
- 1638
- UniProt ID
- P40126
Downloads
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