PE-A*02:01/Human MC1R (GLVSLVENA) MHC Tetramer
CAT#: MHC-LC2678
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human MC1R of peptide GLVSLVENA covering 49-57 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (MCF7, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000258839-MC1R
❮
❯
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MC1R
- Antigen Species
- Human
- Peptide
- GLVSLVENA
- Range
- 49-57
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008]
- Alternative Names
- MC1R; Melanocyte-stimulating hormone receptor; CMM5; MSH-R; SHEP2
- Gene ID
- 4157
- UniProt ID
- Q01726
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MHC-LC2678. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MC1R"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2308z | Mouse Anti-MC1R Recombinant Antibody (clone 40A1) | WB, IHC | Mouse IgM |
| CBPAB-037LC | Rabbit Anti-MC1R Polyclonal Antibody | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-006 | Recombinant Anti-human MC1R VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L082D | MSH-DT immunotoxin | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2185 | Hi-Affi™ Recombinant Rabbit Anti-MC1R Monoclonal Antibody (DS2185AB) | WB, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX760 | Mouse Anti-MC1R Recombinant Antibody (clone 578CT6.2.3) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4289 | Anti-MC1R Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA, IP, WB, IHC, IF, FuncS
Application: ELISA, SPR, Inhib, FuncS
-2.jpg)
Application: IB, ELISA, FC, FuncS
Application: FC, IB, Block, Inhib, FuncS, ELISA, FACS, IP, IF
-5.jpg)
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, Activ, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
