PE-A*02:01/Human PSMB3 (GLATDVQTV) MHC Tetramer (CAT#: MHC-LC1926)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PSMB3 of peptide GLATDVQTV covering 55-63 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- PSMB3
- Antigen Species
- Human
- Peptide
- GLATDVQTV
- Range
- 55-63
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq, Sep 2013]
- Alternative Names
- PSMB3; Proteasome subunit beta type-3; HC10-II
- Gene ID
- 5691
- UniProt ID
- P49720
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See other products for "PSMB3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3423z | Mouse Anti-PSMB3 Recombinant Antibody (clone 39H12) | IP, WB, FuncS | Mouse IgG1 |
| MOB-2411CT | Recombinant Mouse anti-Human PSMB3 Monoclonal antibody (MCP102) | IHC-P, WB |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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