PE-A*02:01/Human SNRPA (NQFPGFKEV) MHC Tetramer

CAT#: MHC-LC1938

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human SNRPA of peptide NQFPGFKEV covering 229-237 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IF staining of human cell line U-251 MG Figure 2 IF staining of human cell line A-431 Figure 3 Lymph node Figure 4 Cerebral cortex Figure 5 Colon Figure 6 Liver Figure 7 Kidney Figure 8 RNA cell line category: Low cell line specificity

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • SNRPA
  • Antigen Species
  • Human
  • Peptide
  • NQFPGFKEV
  • Range
  • 229-237
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]
  • Alternative Names
  • SNRPA; U1 small nuclear ribonucleoprotein A; U1A; Mud1; U1-A
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