PE-A*02:06/Human HNRNPK (ILKKIIPTL) MHC Tetramer (CAT#: MHC-LC3862)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HNRNPK of peptide ILKKIIPTL covering 100-108 and A*02:06 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:06
  • Class
  • Class I
  • Antigen
  • HNRNPK
  • Antigen Species
  • Human
  • Peptide
  • ILKKIIPTL
  • Range
  • 100-108
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • HNRNPK; Heterogeneous nuclear ribonucleoprotein K; AUKS; CSBP; TUNP; HNRPK

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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