PE-A*11:01/Human CFH (CSDDGFWSK) MHC Tetramer (CAT#: MHC-LC4400)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CFH of peptide CSDDGFWSK covering 192-200 and A*11:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*11:01
  • Class
  • Class I
  • Antigen
  • CFH
  • Antigen Species
  • Human
  • Peptide
  • CSDDGFWSK
  • Range
  • 192-200
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]
  • Alternative Names
  • CFH; Complement factor H; FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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