PE-A*24:02/Human CA9 (EYRALQLHL) MHC Tetramer
CAT#: MHC-LC175
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Carbonic Anhydrase 9-derived peptide of EYRALQLHL sequence covering 219-227 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 Immunofluorescent staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5100/639_D5_2_selected.jpg
Normal Tissue
Figure 2 Stomach
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55207/139851_A_5_1.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (A-431, HDLM-2, hTERT-RPE1, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107159-CA9
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Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- Carbonic Anhydrase 9
- Antigen Species
- Human
- Peptide
- EYRALQLHL
- Range
- 219-227
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
- Alternative Names
- CA9; carbonic anhydrase 9; MN; CAIX
- Gene ID
- 911829
- UniProt ID
- Q05320
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-707 | Anti-CAIX/CA9 Recombinant Antibody (Girentuximab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| TAB-H43 | Anti-Human CA9 Recombinant Antibody (TAB-H43) | ELISA, IP, IF, Inhib | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1456CL | Anti-Human CA9 Recombinant Antibody (MSC1) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1457CL | Anti-Human CA9 Recombinant Antibody (MSC2) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1459CL | Anti-Human CA9 Recombinant Antibody (MSC4) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1460CL | Anti-Human CA9 Recombinant Antibody (MSC5) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1461CL | Anti-Human CA9 Recombinant Antibody (MSC6) | ELISA, FC, Inhib | Fully human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1458CL-S(P) | Anti-Human CA9 Recombinant Antibody (MSC3); scFv Fragment | FC | Human scFv |
| HPAB-0104-LSX-S(P) | Human Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0104-LSX-S(P)) | ELISA | Human scFv |
| HPAB-0105-LSX-S(P) | Human Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0105-LSX-S(P)) | ELISA | Human scFv |
| HPAB-1174WJ-S(P) | Mouse Anti-CA9 Recombinant Antibody (clone AB-MN-21.5.2); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1175WJ-S(P) | Mouse Anti-CA9 Recombinant Antibody (clone AB-MN-21.6.1); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1458CL-F(E) | Anti-Human CA9 Recombinant Antibody (MSC3); Fab Fragment | FC | Human Fab |
| HPAB-0104-LSX-F(E) | Human Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0104-LSX-F(E)) | ELISA | Human Fab |
| HPAB-0105-LSX-F(E) | Human Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0105-LSX-F(E)) | ELISA | Human Fab |
| HPAB-1174WJ-F(E) | Mouse Anti-CA9 Recombinant Antibody (clone AB-MN-21.5.2); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1175WJ-F(E) | Mouse Anti-CA9 Recombinant Antibody (clone AB-MN-21.6.1); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC176 | APC-A*24:02/Human CA9 (EYRALQLHL) MHC Tetramer | FCM | |
| MHC-YF351 | A*24:02/Human CA9 (EYRALQLHL) MHC Pentamer | FCM | |
| MHC-YF442 | A*02:01/Human G250 (renal cell carcinoma) (HLSTAFARV) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0427 | Hi-Affi™ Rabbit Anti-CA9 Recombinant Antibody (clone DS427AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0104-LSX | Human Anti-CA9 Recombinant Antibody (HPAB-0104-LSX) | ELISA, FC, Inhib | Human IgG |
| HPAB-0105-LSX | Human Anti-CA9 Recombinant Antibody (HPAB-0105-LSX) | ELISA, FC, Inhib | Human IgG |
| MRO-0229-CN | Rabbit Anti-CA9 Recombinant Antibody (clone CBACN-083) | WB, IHC | Rabbit IgG |
| ZG-0578J | Rabbit Anti-CA9 Recombinant Antibody (clone 4F12) | ELISA, IHC | Rabbit IgG |
| VS7-HM283 | Mouse Anti-CA9 Recombinant Antibody (clone 2D3) | WB, IHC, FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H43 | Afuco™ Anti-CA9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H43) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY37 | AbPlus™ Anti-CA9 Magnetic Beads (12F10) | IP, Protein Purification | |
| VS-0724-YC1029 | AbPlus™ Anti-CA9 Magnetic Beads (VS-0724-YC1029) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY54 | Human Anti-CA9 (clone G37) scFv-Fc Chimera | FC, ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY290 | Anti-CA9 Immunohistochemistry Kit | IHC | |
| VS-0525-XY911 | Anti-Mouse CA9 Immunohistochemistry Kit | IHC | |
| VS-0525-XY912 | Anti-Human CA9 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC94 | Recombinant Anti-CA9 Vesicular Antibody, EV Displayed (VS-0425-YC94) | ELISA, FC, Neut, Cell-uptake |
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