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APC-A1/Human PCNA (ITEDMGHLKY) MHC Tetramer (CAT#: MHC-LC3417)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PCNA of peptide ITEDMGHLKY and A1 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/148/if_selected.jpg
Normal Tissue
Figure 2 Colon
Figure 2 Colon
(Glandular cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30523/64162_A_9_3.jpg
Figure 3 Testis
Figure 3 Testis
(Leydig cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%

Preleptotene spermatocytes
Staining:

Medium

Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30523/64162_A_6_6.jpg
Figure 4 Bone marrow
Figure 4 Bone marrow
(Hematopoietic cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30523/64162_B_5_4.jpg
Figure 5 Lymph node
Figure 5 Lymph node
(Germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30523/64162_A_7_8.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132646-PCNA
Figure 6 RNA cell line category: Low cell line specificity
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132646-PCNA

Specifications

  • Allele
  • A1
  • Class
  • Class I
  • Antigen
  • PCNA
  • Antigen Species
  • Human
  • Peptide
  • ITEDMGHLKY
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
  • Alternative Names
  • PCNA; proliferating cell nuclear antigen; ATLD2

Downloads

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scFv Fragment Antibody

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Fab Fragment Antibody

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Recombinant Antibody

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HPAB-N0376-YC Mouse Anti-PCNA Recombinant Antibody (HPAB-N0376-YC) ELISA, FC, WB Mouse IgG
MOB-0173F Mouse Anti-PCNA Recombinant Antibody (clone 12D10), AbFluor™ 350 WB, IF, IHC-P Mouse IgG
MOB-0174F Mouse Anti-PCNA Recombinant Antibody (clone 12D10), AbFluor™ 405 WB, IF, IHC-P Mouse IgG
MOB-0175F Mouse Anti-PCNA Recombinant Antibody (clone 12D10), AbFluor™ 488 WB, IF, IHC-P Mouse IgG
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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