PE-A2/Human COL4A5 (SLWGQPAEA) MHC Tetramer (CAT#: MHC-LC1951)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human COL4A5 of peptide SLWGQPAEA covering 18-26 and A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77177/1975_E11_3_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77177/1975_E11_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HeLa, HHSteC, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188153-COL4A5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188153-COL4A5
Specifications
- Allele
- A2
- Class
- Class I
- MHC Species
- Human
- Antigen
- COL4A5
- Antigen Species
- Human
- Peptide
- SLWGQPAEA
- Range
- 18-26
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
- Alternative Names
- COL4A5; Collagen alpha-5(IV) chain; ATS; ASLN; CA54
- Gene ID
- 1287
- UniProt ID
- P29400
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2325z | Mouse Anti-COL4A5 Recombinant Antibody (clone 40A9) | WB, ELISA, ICC, IHC, IP | Mouse IgG1 |
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