PE-B*15:16/Human CR2 (VSYGSIVTY) MHC Tetramer
CAT#: MHC-LC3372
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CR2 of peptide VSYGSIVTY covering 295-303 and B*15:16 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_8_8.jpg
Normal Tissue
Figure 2 Tonsil
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52942/139626_A_4_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (Daudi, JURKAT, MOLT-4, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117322-CR2
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Specifications
- Allele
- B*15:16
- Class
- Class I
- MHC Species
- Human
- Antigen
- CR2
- Antigen Species
- Human
- Peptide
- VSYGSIVTY
- Range
- 295-303
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
- Alternative Names
- CR2; CR2/CD21/C3d/Epstein-Barr virus receptor precursor; CR; C3DR; CD21; CVID7; SLEB9
- Gene ID
- 1380
- UniProt ID
- P20023
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Datasheet
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COA
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