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  • PE-B*27:05/Human PSMB1 (RRFFPYYVY) MHC Tetramer

PE-B*27:05/Human PSMB1 (RRFFPYYVY) MHC Tetramer (CAT#: MHC-LC4418)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PSMB1 of peptide RRFFPYYVY covering 127-135 and B*27:05 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line Hep G2
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29635/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Low cell line specificity
Figure 2 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008018-PSMB1/subcellular

Specifications

  • Allele
  • B*27:05
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • PSMB1
  • Antigen Species
  • Human
  • Peptide
  • RRFFPYYVY
  • Range
  • 127-135
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • PSMB1; Proteasome subunit beta type-1 precursor; HC5; PSC5; PMSB1

Downloads

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Recombinant Antibody

CAT Product Name Application Type
MOB-3342z Mouse Anti-PSMB1 Recombinant Antibody (clone 40G2) WB, IP, IF, IHC, ELISA Mouse IgG1

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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