PE-B*44:03/Human SNX5 (EEPTVIKKY) MHC Tetramer (CAT#: MHC-LC1247)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of SNX5-derived peptide of EEPTVIKKY covering 257-265 and B*44:03 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76450/1816_H7_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76450/1816_H7_1_selected.jpg
Figure 2 IHC staining of human thyroid gland
(Immunohistochemical staining of human thyroid gland shows moderate cytoplasmiuc positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_B_1_5_selected.jpg
(Immunohistochemical staining of human thyroid gland shows moderate cytoplasmiuc positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_B_1_5_selected.jpg
Figure 3 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20679/ihc_selected.jpg
(Immunohistochemical staining of human duodenum shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20679/ihc_selected.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_8_3.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_7_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_6_6.jpg
Figure 7 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_8_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (Hep G2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089006-SNX5
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089006-SNX5
Specifications
- Allele
- B*44:03
- Class
- Class I
- MHC Species
- Human
- Antigen
- SNX5
- Antigen Species
- Human
- Peptide
- EEPTVIKKY
- Range
- 257-265
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Alternative Names
- SNX5; sorting nexin 5
- Gene ID
- 27131
- UniProt ID
- Q9Y5X3
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1248 | APC-B*44:03/Human SNX5 (EEPTVIKKY) MHC Tetramer | FCM | |
| MHC-LC1249 | BV421-B*44:03/Human SNX5 (EEPTVIKKY) MHC Tetramer | FCM |
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