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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    PE-B*44:03/Human SNX5 (EEPTVIKKY) MHC Tetramer (CAT#: MHC-LC1247)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of SNX5-derived peptide of EEPTVIKKY covering 257-265 and B*44:03 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
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    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line Hep G2
    Figure 1 IF staining of human cell line Hep G2
    (Immunofluorescent staining of human cell line Hep G2 shows localization to cytosol & vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/76450/1816_H7_1_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human thyroid gland
    Figure 2 IHC staining of human thyroid gland
    (Immunohistochemical staining of human thyroid gland shows moderate cytoplasmiuc positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_B_1_5_selected.jpg
    Figure 3 IHC staining of human duodenum
    Figure 3 IHC staining of human duodenum
    (Immunohistochemical staining of human duodenum shows strong positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20679/ihc_selected.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_8_3.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_7_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_6_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/51187/130224_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (Hep G2)
    Figure 8 RNA cell line category: Cell line enhanced (Hep G2)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089006-SNX5

    Specifications

    • Allele
    • B*44:03
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • SNX5
    • Antigen Species
    • Human
    • Peptide
    • EEPTVIKKY
    • Range
    • 257-265
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms.
    • Alternative Names
    • SNX5; sorting nexin 5

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