PE-B*58:01/Human PSMA2 (DPSGAYFAW) MHC Tetramer
CAT#: MHC-LC4420
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PSMA2 of peptide DPSGAYFAW covering 150-158 and B*58:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- B*58:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- PSMA2
- Antigen Species
- Human
- Peptide
- DPSGAYFAW
- Range
- 150-158
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]
- Alternative Names
- PSMA2; Proteasome subunit alpha type-2; MU; HC3; PSC2; PMSA2
- Gene ID
- 5683
- UniProt ID
- P25787
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