PE-B7/Human HIST1H1D (AASKERSGVSL) MHC Tetramer

CAT#: MHC-LC1975

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HIST1H1D of peptide AASKERSGVSL covering 50-60 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Colon Figure 3 Liver Figure 4 Kidney Figure 5 Testis Figure 6 Lymph node Figure 7 RNA cell line category: Cell line enhanced (BEWO, MOLT-4, NB-4, REH, SiHa, U-266/70)

Specifications

  • Allele
  • B7
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • HIST1H1D
  • Antigen Species
  • Human
  • Peptide
  • AASKERSGVSL
  • Range
  • 50-60
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
  • Alternative Names
  • HIST1H1D; Histone H1.3; H1D; H1.3; H1F3; H1s-2
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