PE-B7/Human PTPN6 (VPSEPGGVL) MHC Tetramer (CAT#: MHC-LC1966)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PTPN6 of peptide VPSEPGGVL covering 422-430 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- B7
- Class
- Class I
- Antigen
- PTPN6
- Antigen Species
- Human
- Peptide
- VPSEPGGVL
- Range
- 422-430
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
- Alternative Names
- PTPN6; Tyrosine-protein phosphatase non-receptor type 6; HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
- Gene ID
- 5777
- UniProt ID
- P29350
Downloads
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See other products for "PTPN6"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1369CT | Recombinant Mouse anti-Human PTPN6 Monoclonal antibody (2TI02 (22E8D9I6)) | IP, WB | |
| MRO-1389-CN | Recombinant Mouse Anti-PTPN6 Monoclonal Antibody (B5-A4) | WB, IF, IHC | Mouse IgG2b |
| MRO-1390-CN | Recombinant Rabbit Anti-PTPN6 Monoclonal Antibody (CBACN-501) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-CJ856 | Rabbit Anti-PTPN6 Recombinant Antibody (VS3-CJ856) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS3-FY1226 | Recombinant Rabbit Anti-PTPN6 Antibody (clone R08-1A0) | WB | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2931 | Hi-Affi™ Recombinant Rabbit Anti-PTPN6 Monoclonal Antibody (DS2931AB) | ICC/IF, WB, IHC-P, FC, IP | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0535-FY-S(P) | Mouse Anti-PTPN6 Recombinant Antibody; scFv Fragment (HPAB-0535-FY-S(P)) | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0535-FY-F(E) | Mouse Anti-PTPN6 Recombinant Antibody; Fab Fragment (HPAB-0535-FY-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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