PE-B7/Human PTPN6 (VPSEPGGVL) MHC Tetramer
CAT#: MHC-LC1966
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PTPN6 of peptide VPSEPGGVL covering 422-430 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- B7
- Class
- Class I
- MHC Species
- Human
- Antigen
- PTPN6
- Antigen Species
- Human
- Peptide
- VPSEPGGVL
- Range
- 422-430
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
- Alternative Names
- PTPN6; Tyrosine-protein phosphatase non-receptor type 6; HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
- Gene ID
- 5777
- UniProt ID
- P29350
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1369CT | Recombinant Mouse anti-Human PTPN6 Monoclonal antibody (2TI02 (22E8D9I6)) | IP, WB | |
| MRO-1389-CN | Recombinant Mouse Anti-PTPN6 Monoclonal Antibody (B5-A4) | WB, IF, IHC | Mouse IgG2b |
| MRO-1390-CN | Recombinant Rabbit Anti-PTPN6 Monoclonal Antibody (CBACN-501) | WB, IF, IHC, IP, FC | Rabbit IgG |
| HPAB-0535-FY | Mouse Anti-PTPN6 Recombinant Antibody (HPAB-0535-FY) | ELISA | Mouse IgG |
| VS3-QX941 | Mouse Anti-PTPN6 Recombinant Antibody (clone 2B7-H7-F8) | WB, IP | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2931 | Hi-Affi™ Recombinant Rabbit Anti-PTPN6 Monoclonal Antibody (DS2931AB) | ICC, IF, WB, IHC-P, FC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0535-FY-S(P) | Mouse Anti-PTPN6 Recombinant Antibody; scFv Fragment (HPAB-0535-FY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0535-FY-F(E) | Mouse Anti-PTPN6 Recombinant Antibody; Fab Fragment (HPAB-0535-FY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC284 | AbPlus™ Anti-PTPN6 Magnetic Beads (VS-0724-YC284) | IP, Protein Purification | |
| VS-0724-YC1337 | AbPlus™ Anti-Ptpn6 Magnetic Beads (VS-0724-YC1337) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1824 | Anti-PTPN6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5867 | Anti-Mouse PTPN6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5866 | Anti-Human PTPN6 Immunohistochemistry Kit | IHC |
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