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PE-B7/Human TIMP1 (APFEPLASGIL) MHC Tetramer (CAT#: MHC-LC1976)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TIMP1 of peptide APFEPLASGIL covering 2-12 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22360/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human prostate
Figure 2 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/ihc_selected.jpg
Figure 3 Kidney
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_7_5.jpg
Figure 4 Prostate
Figure 4 Prostate
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_2_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000102265-TIMP1

Specifications

  • Allele
  • B7
  • Class
  • Class I
  • Antigen
  • TIMP1
  • Antigen Species
  • Human
  • Peptide
  • APFEPLASGIL
  • Range
  • 2-12
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
  • Alternative Names
  • TIMP1; TIMP metallopeptidase inhibitor 1; EPA; EPO; HCI; CLGI; TIMP; TIMP-1

Downloads

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See other products for "TIMP1"

Recombinant Antibody

CAT Product Name Application Type
MOB-1378z Mouse Anti-TIMP1 Recombinant Antibody (clone 39D12) WB, ELISA Mouse IgG1
HPAB-0174-YC Human Anti-TIMP1 Recombinant Antibody (clone HuCAL) ELISA Human IgG
ZG-0125C Mouse Anti-TIMP1 Recombinant Antibody (clone PT2236) IHC-P, IF Mouse IgG
ZG-0705F Mouse Anti-TIMP1 Recombinant Antibody (clone 2A5) WB, ELISA, IHC Mouse IgG1
VS3-FY1455 Recombinant Mouse Anti-TIMP1 Antibody (clone 5H5-6G1-2E1) IHC-P Mouse IgG1

Human Antibody

CAT Product Name Application Type
TAB-683CT Anti-Human TIMP-1 Recombinant Antibody (MS-BW-3 ) ELISA, BL Human antibody
TAB-683CT-S(P) Anti-Human TIMP-1 Recombinant Antibody scFv Fragment (MS-BW-3 ) ELISA, BL Human antibody
TAB-684CT-S(P) Anti-Human TIMP-1 Recombinant Antibody scFv Fragment (MS-BW-28) ELISA, BL Human antibody
TAB-685CT-S(P) Anti-Human TIMP-1 Recombinant Antibody scFv Fragment (MS-BW-1) ELISA, BL Human antibody
TAB-686CT-S(P) Anti-Human TIMP-1 Recombinant Antibody scFv Fragment (MS-BW-27) ELISA, BL Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3575 Rabbit Anti-TIMP1 Recombinant Antibody (clone DS3575AB) WB Rabbit IgG
MOR-4458 Rabbit Anti-TIMP1 Recombinant Antibody (clone SI552DS) ELISA Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0174-YC-S(P) Human Anti-TIMP1 Recombinant Antibody (clone HuCAL); scFv Fragment ELISA Human scFv
HPAB-0192-WJ-S(P) Human Anti-TIMP1 Recombinant Antibody; scFv Fragment (HPAB-0192-WJ-S(P)) ELISA Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0174-YC-F(E) Human Anti-TIMP1 Recombinant Antibody (clone HuCAL); Fab Fragment ELISA Human Fab
HPAB-0192-WJ-F(E) Human Anti-TIMP1 Recombinant Antibody; Fab Fragment (HPAB-0192-WJ-F(E)) ELISA Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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