PE-B7/Human TIMP1 (APFEPLASGIL) MHC Tetramer
CAT#: MHC-LC1976
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TIMP1 of peptide APFEPLASGIL covering 2-12 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/22360/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human prostate
Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/ihc_selected.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_7_5.jpg
Normal Tissue
Figure 4 Prostate
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_2_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000102265-TIMP1
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Specifications
- Allele
- B7
- Class
- Class I
- MHC Species
- Human
- Antigen
- TIMP1
- Antigen Species
- Human
- Peptide
- APFEPLASGIL
- Range
- 2-12
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
- Alternative Names
- TIMP1; TIMP metallopeptidase inhibitor 1; EPA; EPO; HCI; CLGI; TIMP; TIMP-1
- Gene ID
- 7076
- UniProt ID
- P01033
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1378z | Mouse Anti-TIMP1 Recombinant Antibody (clone 39D12) | WB, ELISA | Mouse IgG1 |
| HPAB-0174-YC | Human Anti-TIMP1 Recombinant Antibody (clone HuCAL) | ELISA | Human IgG |
| HPAB-0192-WJ | Human Anti-TIMP1 Recombinant Antibody (HPAB-0192-WJ) | ELISA | Human IgE |
| ZG-0125C | Mouse Anti-TIMP1 Recombinant Antibody (clone PT2236) | IHC-P, IF | Mouse IgG |
| ZG-0126C | Mouse Anti-TIMP1 Recombinant Antibody (clone ABT-TIMP1) | IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-683CT-S(P) | Anti-Human TIMP-1 Recombinant Antibody scFv Fragment (MS-BW-3 ) | ELISA, BL | Human antibody |
| TAB-683CT-F(E) | Anti-Human TIMP-1 Recombinant Antibody Fab Fragment (MS-BW-3 ) | ELISA, BL | Human antibody |
| TAB-684CT-F(E) | Anti-Human TIMP-1 Recombinant Antibody Fab Fragment (MS-BW-28) | ELISA, BL | Human antibody |
| TAB-685CT-F(E) | Anti-Human TIMP-1 Recombinant Antibody Fab Fragment (MS-BW-1) | ELISA, BL | Human antibody |
| TAB-686CT-F(E) | Anti-Human TIMP-1 Recombinant Antibody Fab Fragment (MS-BW-27) | ELISA, BL | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3575 | Rabbit Anti-TIMP1 Recombinant Antibody (clone DS3575AB) | WB | Rabbit IgG |
| MOR-4458 | Rabbit Anti-TIMP1 Recombinant Antibody (clone SI552DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0174-YC-S(P) | Human Anti-TIMP1 Recombinant Antibody (clone HuCAL); scFv Fragment | ELISA | Human scFv |
| HPAB-0192-WJ-S(P) | Human Anti-TIMP1 Recombinant Antibody; scFv Fragment (HPAB-0192-WJ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0174-YC-F(E) | Human Anti-TIMP1 Recombinant Antibody (clone HuCAL); Fab Fragment | ELISA | Human Fab |
| HPAB-0192-WJ-F(E) | Human Anti-TIMP1 Recombinant Antibody; Fab Fragment (HPAB-0192-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY147 | Human Anti-TIMP1 (clone mab1) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7268 | Anti-TIMP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7269 | Anti-Mouse TIMP1 Immunohistochemistry Kit | IHC |
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