PE-B7/Human TNFRSF13B (SPALPGLKL) MHC Tetramer
CAT#: MHC-LC1968
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TNFRSF13B of peptide SPALPGLKL covering 147-155 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30453/66589_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Peripheral nerve/ganglion
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30453/66589_A_9_3.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30453/66589_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30453/66589_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30453/66589_A_4_6.jpg
Normal Tissue
Figure 6 Appendix
Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Lymphoid tissue
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30453/66589_A_1_2.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30453/66589_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (Karpas-707, RPMI-8226, U-266/70)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 8 RNA cell line category: Group enriched (Karpas-707, RPMI-8226, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000240505-TNFRSF13B
❮
❯
Specifications
- Allele
- B7
- Class
- Class I
- MHC Species
- Human
- Antigen
- TNFRSF13B
- Antigen Species
- Human
- Peptide
- SPALPGLKL
- Range
- 147-155
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
- Alternative Names
- TNFRSF13B; Tumor necrosis factor receptor superfamily member 13B; CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B
- Gene ID
- 23495
- UniProt ID
- O14836
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Datasheet
MSDS
COA
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Lot Number:
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| CAT | Product Name | Application | Type |
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