PE-DQB1*03:02/Human PTPRN (GVAGLLVALAV) MHC Tetramer (CAT#: MHC-LC3240)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PTPRN of peptide GVAGLLVALAV covering 586-596 and DQB1*03:02 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- DQB1*03:02
- Class
- Class II
- MHC Species
- Human
- Antigen
- PTPRN
- Antigen Species
- Human
- Peptide
- GVAGLLVALAV
- Range
- 586-596
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
- Alternative Names
- PTPRN; Receptor-type tyrosine-protein phosphatase-like N precursor; IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP
- Gene ID
- 5798
- UniProt ID
- Q16849
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-828 | Recombinant Anti-human PTPRN Antibody | ELISA, IF, FuncS | IgG |
| MHH-828 | Recombinant Human Anti-human PTPRN Antibody | ELISA, WB, FC, FuncS | IgG |
| MOB-0419ZL | Rabbit anti- PTPRN Polyclonal Antibody | WB | |
| VS-0823-LC4 | Mouse Anti-PTPRN Recombinant Antibody (VS-0823-LC4) | ELISA, WB, IHC | Mouse IgG2a |
| VS-0823-LC5 | Mouse Anti-PTPRN Recombinant Antibody (VS-0823-LC5) | ELISA, WB, IHC, IF | Mouse IgG3 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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