PE-DRB1*04:01/Human CHRNA1 (DTPYLDITYHFVMQRLPL) MHC Tetramer (CAT#: MHC-LC2114)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CHRNA1 of peptide DTPYLDITYHFVMQRLPL covering 240-257 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/1417_F4_2_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/1417_F4_2_selected.jpg
Figure 2 IF staining of human cell line LHCN-M2
(Immunofluorescent staining of human cell line LHCN-M2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/1781_A4_31_blue_red_green.jpg
(Immunofluorescent staining of human cell line LHCN-M2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/1781_A4_31_blue_red_green.jpg
Figure 3 Skeletal muscle
(Myocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/165026_B_2_6.jpg
(Myocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/165026_B_2_6.jpg
Figure 4 RNA cell line category: Group enriched (LHCN-M2, RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138435-CHRNA1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138435-CHRNA1
Figure 4 RNA cell line category: Group enriched (LHCN-M2, RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138435-CHRNA1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138435-CHRNA1
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- CHRNA1
- Antigen Species
- Human
- Peptide
- DTPYLDITYHFVMQRLPL
- Range
- 240-257
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]
- Alternative Names
- CHRNA1; Acetylcholine receptor subunit alpha precursor; ACHRA; ACHRD; CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; SCCMS
- Gene ID
- 1134
- UniProt ID
- P02708
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|---|---|---|---|
| MOB-1267z | Mouse Anti-CHRNA1 Recombinant Antibody (clone 25F9) | WB, ICC, IF, IHC, IP | Mouse IgG1 |
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| PABS-0058 | Rat Anti-Chrna1 Recombinant Antibody (Clone Fab35) | ELISA, FuncS | Rat IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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