APC-DRB1*04:02/Human CD74 (MHHWLLFEMSRHSLE) MHC Tetramer (CAT#: MHC-LC3349)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CD74 of peptide MHHWLLFEMSRHSLE covering 185-199 and DRB1*04:02 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Allele
  • DRB1*04:02
  • Class
  • Class II
  • Antigen
  • CD74
  • Antigen Species
  • Human
  • Peptide
  • MHHWLLFEMSRHSLE
  • Range
  • 185-199
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Alternative Names
  • CD74; HLA class II histocompatibility antigen gamma chain; II; DHLAG; HLADG; Ia-GAMMA

Downloads

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See other products for "CD74"

Single-domain Antibody

CAT Product Name Application Type
TAB-0004CL-VHH Anti-Human CD74 VHH Single Domain Antibody (NbhCD74n49 (Nb_49)) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0005CL-VHH Anti-Human CD74 VHH Single Domain Antibody (NbhCD74n95 (Nb_95)) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0006CL-VHH Anti-Human CD74 VHH Single Domain Antibody (Nb_03) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0007CL-VHH Anti-Human CD74 VHH Single Domain Antibody (Nb_04) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0008CL-VHH Anti-Human CD74 VHH Single Domain Antibody (Nb_05) ELISA, FC, Internalization, Inhib, FuncS VHH

Blocking Antibody

CAT Product Name Application Type
NEUT-408CQ Mouse Anti-CD74 Recombinant Antibody (clone LN2) FC, IHC-Fr, IHC-P, ICC, IP, WB, Block Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0579 Hi-Affi™ Rabbit Anti-CD74 Recombinant Antibody (clone DS579AB) ICC, IHC-P, IP, WB Rabbit IgG

scFv Fragment Antibody

Fab Fragment Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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