PE-DRB1*11:01/Human CHRNA1 (DTPYLDITYHFVMQRLPL) MHC Tetramer
CAT#: MHC-LC2116
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CHRNA1 of peptide DTPYLDITYHFVMQRLPL covering 240-257 and DRB1*11:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/1417_F4_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line LHCN-M2
Immunofluorescent staining of human cell line LHCN-M2 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/1781_A4_31_blue_red_green.jpg
Normal Tissue
Figure 3 Skeletal muscle
Myocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71554/165026_B_2_6.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (LHCN-M2, RH-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138435-CHRNA1
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Specifications
- Allele
- DRB1*11:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- CHRNA1
- Antigen Species
- Human
- Peptide
- DTPYLDITYHFVMQRLPL
- Range
- 240-257
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]
- Alternative Names
- CHRNA1; Acetylcholine receptor subunit alpha precursor; ACHRA; ACHRD; CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; SCCMS
- Gene ID
- 1134
- UniProt ID
- P02708
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| CAT | Product Name | Application | Type |
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| PSBZ-149 | Recombinant Rat Anti-T. californica CHRNA1 Antibody scFv Fragment (mAb6) | WB | scFv |
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| CAT | Product Name | Application | Type |
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