PE-DRB1*13:01/Human HLA-B (GPDGRLLRGHDQYAYDGKDY) MHC Tetramer
CAT#: MHC-LC3359
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HLA-B of peptide GPDGRLLRGHDQYAYDGKDY covering 128-147 and DRB1*13:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15418/35903_B_9_5.jpg
Normal Tissue
Figure 2 Colon
Endocrine cells
Staining: High
Intensity: Strong
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15418/35903_A_8_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15418/35903_A_7_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15418/35903_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15418/35903_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15418/35903_A_9_8.jpg
Normal Tissue
Figure 7 Spleen
Cells in red pulp
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15418/35903_B_9_4.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (A-431, EFO-21, U-266/70, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000234745-HLA-B
❮
❯
Specifications
- Allele
- DRB1*13:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- HLA-B
- Antigen Species
- Human
- Peptide
- GPDGRLLRGHDQYAYDGKDY
- Range
- 128-147
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]
- Alternative Names
- HLA-B; HLA class I histocompatibility antigen, B-7 alpha chain precursor; AS; HLAB; B-4901
- Gene ID
- 3106
- UniProt ID
- P01889
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MHC-LC3359. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "HLA-B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1618 | Rabbit Anti-HLA-B Recombinant Antibody (clone DS1618AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1475CQ | Rabbit Anti-HLA-B Recombinant Antibody (clone YTH 76.3) | ELISA | Rabbit IgG |
| VS3-QX532 | Mouse Anti-HLA-B Recombinant Antibody (clone 11C3) | WB, ICC | Mouse IgG1 |
| VS3-QX533 | Mouse Anti-HLA-B Recombinant Antibody (clone 11C2) | WB, ICC, IHC | Mouse IgG1 |
| VS7-0425-WR67 | Mouse Anti-HLA-B Recombinant Antibody (clone 4D4B6) | WB, ELISA | Mouse IgG1 |
| VS7-0425-WR68 | Mouse Anti-HLA-B Recombinant Antibody (clone 2G7B10) | WB, IHC, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX534 | Mouse Anti-HLA-B Recombinant Antibody (clone 528CT10.4.1) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC698 | Recombinant Anti-HLA-B Vesicular Antibody, EV Displayed (VS-0425-YC698) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3165 | Anti-HLA-B Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
-2.png)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
-2-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, Neut, FuncS
Application: ELISA, Inhib, FC
-2.png)
Application: WB, ELISA, FC, IHC, IP
Application: WB, ELISA, Neut, FuncS
Application: ELISA, WB
Application: Inhib, FC, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
