PE-DRB5*01:01/Human PLP1 (MAATYNFAVLKLMGRFTKF) MHC Tetramer (CAT#: MHC-LC2199)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PLP1 of peptide MAATYNFAVLKLMGRFTKF and DRB5*01:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- DRB5*01:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- PLP1
- Antigen Species
- Human
- Peptide
- MAATYNFAVLKLMGRFTKF
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
- Alternative Names
- PLP1; proteolipid protein 1; PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20
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