PE-H-2Kb/Trypanosoma cruzi Trans-sialidase (TcTS) (ANYKFTLV) MHC Tetramer (CAT#: MHC-LC631)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Trypanosoma cruzi-derived peptide of ANYKFTLV sequence covering 380-387 and H-2Kb molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

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Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • H-2Kb
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • Trypanosoma cruzi Trans-sialidase (TcTS)
  • Antigen Species
  • Trypanosoma cruzi
  • Peptide
  • ANYKFTLV
  • Range
  • 380-387
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Trypanosoma cruzi is a species of parasitic euglenoids. Amongst the protozoa, the trypanosomes characteristically bore tissue in another organism and feed on blood (primarily) and also lymph. This behaviour causes disease or the likelihood of disease that varies with the organism: for example, trypanosomiasis in humans (Chagas disease in South America ), dourine and surra in horses, and a brucellosis-like disease in cattle. Parasites need a host body and the haematophagous insect triatomine (descriptions "assassin bug", "cone-nose bug", and "kissing bug") is the major vector in accord with a mechanism of infection. The triatomine likes the nests of vertebrate animals for shelter, where it bites and sucks blood for food. Individual triatomines infected with protozoa from other contact with animals transmit trypanosomes when the triatomine deposits its faeces on the host's skin surface and then bites. Penetration of the infected faeces is further facilitated by the scratching of the bite area by the human or animal host.
  • Alternative Names
  • T. cruzi TcTS; Trypanosoma cruzi Trans-sialidase

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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