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    PE-HLA-DR1/Human CLIP (KPVSKWRMATPLLMQALPM) MHC Tetramer (CAT#: MHC-LC923)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CLIP-derived peptide of KPVSKWRMATPLLMQALPM covering 102-120 and HLA-DR1 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line SiHa
    Figure 1 IF staining of human cell line SiHa
    (Immunofluorescent staining of human cell line SiHa shows localization to microtubule ends.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human placenta
    Figure 2 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/ihc_selected.jpg
    Figure 3 IHC staining of human prostate
    Figure 3 IHC staining of human prostate
    (Immunohistochemical staining of human prostate shows strong cytoplasmic and nuclear positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4399/ihc_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_B_9_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_A_9_3.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_A_7_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_A_4_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130779-CLIP1

    Specifications

    • Allele
    • HLA-DR1
    • Class
    • Class II
    • MHC Species
    • Human
    • Antigen
    • CLIP
    • Antigen Species
    • Human
    • Peptide
    • KPVSKWRMATPLLMQALPM
    • Range
    • 102-120
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.
    • Alternative Names
    • CLIP1; CAP-Gly domain containing linker protein 1; RSN; CLIP; CYLN1; CLIP170; CLIP-170

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    Please select product type
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    CAT Product Name Application Type
    MHC-LC924 APC-HLA-DR1/Human CLIP (KPVSKWRMATPLLMQALPM) MHC Tetramer FCM
    MHC-LC925 BV421-HLA-DR1/Human CLIP (KPVSKWRMATPLLMQALPM) MHC Tetramer FCM

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