Palifermin (CAT#: TP-060CL)
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli.
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/1150_E6_2_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/1150_E6_2_selected.jpg
Figure 2 IHC staining of human stomach, upper
(Immunohistochemical staining of human stomach, upper shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/ihc_selected.jpg
(Immunohistochemical staining of human stomach, upper shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/ihc_selected.jpg
Figure 3 Esophagus
(Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/96645_B_6_1.jpg
(Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/96645_B_6_1.jpg
Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/96645_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43605/96645_A_9_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ, fHDF/TERT166, HSkMC, RH-30, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140285-FGF7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140285-FGF7
Specifications
- Classify
- Protein therapeutics augmenting an existing pathway: Growth regulation
- Therapeutic
- Palifermin (keratinocyte growth factor; KGF)
- Trade Name
- Kepivance
- Function
- Recombinant analogue of KGF; stimulates keratinocyte growth in skin, mouth, stomach and colon
- Examples of clinical use
- Severe oral mucositis in patients undergoing chemotherapy
References
- Synonyms
- FGF-7, Fibroblast growth factor- 7, HBGF-7, Keratinocyte growth factor precursor, KGF
- UniProt
- P21781
- Genbank
- M60828
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0107CT | Recombinant Mouse anti-Human FGF7 Monoclonal antibody (2.B.30) | ELISA, WB | |
| VS3-FY548 | Recombinant Rabbit Anti-FGF7 Antibody (clone R07-5C6) | WB | Rabbit IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-818CQ | Mouse Anti-FGF7 Recombinant Antibody (clone CBL132) | Neut, WB | Mouse IgG1 |
| NEUT-819CQ | Mouse Anti-FGF7 Recombinant Antibody (clone CBL447) | ELISA, Neut | Mouse IgG1 |
| NEUT-820CQ | Mouse Anti-FGF7 Recombinant Antibody (clone MM0436-12Z7) | WB, Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1295 | Hi-Affi™ Rabbit Anti-FGF7 Recombinant Antibody (clone DS1295AB) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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