Human Anti-RSV F Recombinant Antibody (TP-098CL)
CAT#: TP-098CL
Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). This antibody is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains of human IgG1 and the variable framework regions of the VH genes Cor (1) and Cess (2). The human light chain sequence was derived from the constant domain of Ck and the variable framework regions of the VL gene K104 withJk-4. The antibody is expressed from a stable murine (mouse) myeloma cell line (NS0).It is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa.
Specifications
- Type
- Biotech
Target
- Function
- Humanized igG1 mAb that binds the A antigenic site of the F protein of respiratory syncytial virus
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Reliable and Super Sensitive
As a scientist working on RSV, I find this antibody extremely sensitive and specific to the F protein, making it perfect for detecting low antigen levels. Its recombinant nature and humanized design enhance its application across various assays. The reliable results bolster my research and data integrity.
Highly Specific for RSV Studies
The humanized recombinant technology ensures minimized cross-reactivity with other proteins, which significantly boosts my research on RSV. It's rare to find an antibody that performs consistently well in both functional studies and neutralization assays. My lab's go-to for RSV-related projects.
Superior Quality and Performance
The quality of this recombinant antibody sets a high bar. Its performance in competitive assays is unparalleled in my experience, allowing for the detection of elusive RSV proteins. It's crucial for my ongoing projects, given the consistently superior outcomes.
Q&As
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Is there any genetic engineering involved in the production of this antibody?
A: Yes, this antibody is produced by recombinant DNA technology, featuring 95% human and 5% murine antibody sequences that enhance specificity and performance consistency.
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Does the antibody contain any endotoxins?
A: The regular batch production does not include endotoxin removal. However, high-purity processes ensure low endotoxin levels suitable for most research applications.
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What makes this antibody ideal for RSV research?
A: Its specificity to the RSV F protein and humanized design make it an excellent tool for studying RSV pathogenesis and developing antiviral strategies.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TP-098CL, RRID: AB_3112054)
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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