Peginterferon alfa-2a (CAT#: TP-039CL)
Human interferon 2a, is a covalent conjugate of recombinant alfa-2a interferon with a single branched bis-monomethoxy polyethylene glycol (PEG) chain. The PEG moiety is linked at a single site to the interferon alfa moiety via a stable amide bond to lysine. Peginterferon alfa-2a has an approximate molecular weight of 60,000 daltons. Interferon alfa-2a is produced using recombinant DNA technology in which a cloned human leukocyte interferon gene is inserted into and expressed in Escherichia coli. The resultant protein is 165 amino acids. The PEG strand protects the molecule in vivo from proteolytic breakdown, substantially increases its in vivo half-life, and reduces immunogenicity by wrapping around and physically hindering access to the protein portion of the molecule.
RNA Expression
Figure 1 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188379-IFNA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188379-IFNA2
Figure 1 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188379-IFNA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188379-IFNA2
Specifications
- Classify
- Protein therapeutics augmenting an existing pathway: Immunoregulation
- Therapeutic
- Peginterferon-α2a
- Trade Name
- Peginterferon alfa-2a
- Function
- Recombinant interferon-a2a conjugated to polyethylene glycol (PeG) to increase half-life
- Examples of clinical use
- Adults with chronic hepatitis c who have compensated liver disease and who have not been previously treated with iFNa; used alone or in combination with ribavirin
References
- Synonyms
- Not Available
- UniProt
- P01563
- Genbank
- J00207
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IFNA2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1175z | Mouse Anti-IFNA2 Recombinant Antibody (clone 33D4) | ELISA, FC, ICC, IF | Mouse IgG1, κ |
| MOB-2029MZ | Recombinant Mouse Anti-Human IFNA2 Antibody (clone O38) | ELISA, ELISA, WB | Mouse antibody |
| HPAB-1731-FY | Mouse Anti-IFNA2 Recombinant Antibody (clone ScFv17) | ELISA | Mouse IgG |
| VS3-WK1744 | Recombinant Rabbit Anti-IFNA2 Capture Antibody (clone R02-2V7) | ELISA | Rabbit IgG |
| VS3-WK1745 | Recombinant Rabbit Anti-IFNA2 Detection Antibody (clone R09-8K4) | ELISA | Rabbit IgG |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0278MZ | Chicken Anti-Interferon α2 Polyclonal IgY | WB, Indirect ELISA | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-965CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone MMHA-11) | ELISA, Neut | Mouse IgG1 |
| NEUT-1065CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone 2-48) | ELISA, IHC-Fr, Neut, WB | Mouse IgG1 |
| NEUT-1066CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone MMHA-1) | ELISA, Neut | Mouse IgG1, κ |
| NEUT-1067CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone CBL230) | ELISA, Neut | Mouse IgG1 |
| NEUT-1068CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone CBL1025) | Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-973CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone N39) | ELISA, Block, WB | Mouse IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0116-LSX-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone 3B7); scFv Fragment | ELISA, EMSA | Mouse scFv |
| HPAB-0117-LSX-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1F3); scFv Fragment | ELISA, EMSA | Mouse scFv |
| HPAB-0118-LSX-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1D3); scFv Fragment | ELISA, EMSA | Mouse scFv |
| HPAB-1731-FY-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone ScFv17); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0116-LSX-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone 3B7); Fab Fragment | ELISA, EMSA | Mouse Fab |
| HPAB-0117-LSX-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1F3); Fab Fragment | ELISA, EMSA | Mouse Fab |
| HPAB-0118-LSX-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1D3); Fab Fragment | ELISA, EMSA | Mouse Fab |
| HPAB-1731-FY-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone ScFv17); Fab Fragment | ELISA | Mouse Fab |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-040CN | Human Anti-IFNA2 Recombinant Antibody (NS-040CN) | ELISA, WB, FC, ADCC | Human IgG |
| NS-040CN-F(E) | Human Anti-IFNA2 Recombinant Antibody; Fab Fragment (NS-040CN-F(E)) | ELISA, WB, FC | Human Fab |
| NS-040CN-S(P) | Human Anti-IFNA2 Recombinant Antibody; scFv Fragment (NS-040CN-S(P)) | ELISA, WB, FC | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TP-039CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.