Recombinant Anti-Human GCC2 Antibody
CAT#: MOB-3017z
Recombinant Mouse Antibody is bind to Human GCC2, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/381_D10_3_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35850/1509_D4_3_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/74610_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/74610_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/74610_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/74610_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/74610_A_6_6.jpg
Normal Tissue
Figure 8 Prostate
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/74610_A_3_5.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35849/74610_A_7_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135968-GCC2
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Specifications
- Immunogen
- Human GRIP And Coiled-Coil Domain Containing 2
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native Human GRIP And Coiled-Coil Domain Containing 2
- Species Reactivity
- Human
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Western blot; Immunofluorescence; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- GCC2; Golgi Coiled-Coil Protein GCC185; GRIP And Coiled-Coil Domain-Containing 2; GRIP And Coiled-Coil Domain Containing 2; REN53; GCC185; Ran-Binding Protein 2-Like 4; KIAA0336; CTCL Tumor Antigen Se1-1; 185 KDa Golgi Coiled-Coil Protein; GCC Protein, 18
- Gene ID
- 9648
- UniProt ID
- Q8IWJ2
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Reliable for Cellular Studies
Our research team has found the Recombinant Anti-Human GCC2 Antibody to be exceptionally reliable for our studies on cellular trafficking. Its specificity and repeatability in immunofluorescence assays have consistently delivered clear and accurate results, playing a crucial role in our experimental setups.
High-Quality and Consistent
This antibody exemplifies high quality with its over 95% purity. It provides consistent results across our Western blot applications, which is vital for verifying GCC2 protein levels in various samples, greatly aiding in our data consistency and reliability.
Enhances Golgi Research
We've been using this antibody in our lab to explore Golgi apparatus dynamics, and it has proven to be invaluable. The binding precision and sensitivity of the antibody facilitate detailed observations, allowing us to derive more meaningful insights into Golgi-related processes.
Q&As
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What is the primary target of the Recombinant Anti-Human GCC2 Antibody?
A: This antibody targets the human GRIP and Coiled-Coil Domain Containing 2 (GCC2), a protein involved in Golgi apparatus function and intracellular transport. It's crucial for studies focusing on cellular trafficking and Golgi-related functions in human cells.
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What is the significance of studying GCC2 in research?
A: GCC2 is pivotal in maintaining Golgi structure and function, playing a role in vesicular trafficking pathways. Understanding its function can lead to insights into intracellular transport mechanisms, cellular organization, and possibly its implications in certain diseases.
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How can this antibody be applied in research studies?
A: The Recombinant Anti-Human GCC2 Antibody is suitable for applications such as Western blotting, immunofluorescence, and enzyme-linked immunosorbent assays (ELISA). These applications help in studying the localization, expression, and function of GCC2 in different cell types.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "GCC2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3017z-F(E) | Recombinant Anti-Human GCC2 Antibody Fab Fragment | IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3017z-S(P) | Recombinant Anti-Human GCC2 Antibody scFv Fragment | FC, WB, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| CBPAB-055LC | Rabbit Anti-GCC2 Polyclonal Antibody | IF, IHC | Rabbit IgG |
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