Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated)
CAT#: Gly-193LC
This product is a non-glycosylated human monoclonal antibody. The antibody has increased efficacy as well as decreased side effect, it specifically binds to human Pac1 and can be potentially used in the treatment of migraine.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30739/1735_E10_1_selected.jpg
Normal Tissue
Figure 2 High expression in cerebral cortex
Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000078549-ADCYAP1R1
❮
❯
Glyco-engineering
- Activity
- Increased efficacy and/or decreased side effects
Specifications
- Target
- Pac1 (Pituitary adenylate cyclase-activating polypeptide type I receptor)
- Host Species
- Human
- Derivation
- XENOMOUSE
- Type
- Human antibody
- Specificity
- Human
- Antibody Isotype
- IgG
- Clone
- 39B
- Applications
- ELISA
Target
- Alternative Names
- ADCYAP1R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC1; PAC1R; PACAPR; PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; PACAP receptor 1; PACAP type I receptor; pituitary adenylate cyc
- Related Disease
- Migraine
- Gene ID
- 117
- UniProt ID
- A0A090N8F8
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3850z | Mouse Anti-ADCYAP1R1 Recombinant Antibody (clone 15H5) | WB, IP, ELISA | Mouse IgG1, κ |
| HPAB-0431-YJ | Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0431-YJ) | Block, FuncS | Human IgG2, κ |
| HPAB-0432-YJ | Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0432-YJ) | Block, FuncS | Human IgG2, κ |
| HPAB-0437YY | Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0437YY) | Inhib, FC | Humanized IgG |
| HPAB-0440YY | Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0440YY) | FC | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0917CL | Anti-Human ADCYAP1R1 Recombinant Antibody (2C) | Competitive ELISA | |
| TAB-0917CL-S(P) | Anti-Human ADCYAP1R1 Recombinant Antibody scFv Fragment (2C) | Competitive ELISA | |
| TAB-0917CL-F(E) | Anti-Human ADCYAP1R1 Recombinant Antibody Fab Fragment (2C) | Competitive ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0918CL | Human Anti-ADCYAP1R1 Recombinant Antibody (TAB-0918CL) | ChIP | Human IgG1 |
| TAB-0919CL | Human Anti-ADCYAP1R1 Recombinant Antibody (TAB-0919CL) | cAMP functional assay | Human IgG2 |
| TAB-0918CL-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (TAB-0918CL-S(P)) | cAMP functional assay | Human scFv |
| TAB-0919CL-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (TAB-0919CL-S(P)) | cAMP functional assay | Human scFv |
| TAB-0918CL-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (TAB-0918CL-F(E)) | cAMP functional assay | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-189LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| Gly-190LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| Gly-191LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| Gly-192LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0039CQ-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0039CQ-S(P)) | ELISA, Block | Human scFv |
| HPAB-0431-YJ-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0431-YJ-S(P)) | Block, FuncS | Human scFv |
| HPAB-0437YY-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0437YY-S(P)) | Neut | Human scFv |
| HPAB-0440YY-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0440YY-S(P)) | Neut | Human scFv |
| HPAB-0444YY-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0444YY-S(P)) | Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0039CQ-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0039CQ-F(E)) | ELISA, Block | Human Fab, κ |
| HPAB-0431-YJ-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0431-YJ-F(E)) | Block, FuncS | Human Fab |
| HPAB-0437YY-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0437YY-F(E)) | Neut | Humanized Fab |
| HPAB-0440YY-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0440YY-F(E)) | Neut | Humanized Fab |
| HPAB-0444YY-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0444YY-F(E)) | Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY7 | AbPlus™ Anti-ADCYAP1R1 Magnetic Beads (VS-0424-XY7) | ChIP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC565 | Recombinant Anti-ADCYAP1R1 Vesicular Antibody, EV Displayed (VS-0425-YC565) | ELISA, FC, Neut, Cell-uptake |
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