Recombinant Anti-Human CD22 Antibody (Fab glycosylation) (CAT#: Gly-001LC)
This product is a mouse monoclonal antibody with N-glycosylation sites in FR1 of VK. The glycan in variable region does not affect the immunoreactivity and can be used for conjugating therapeutic or diagnostic agents. Antibody LL2 specifically binds human CD22 and can be potentially used in the treatment of B-cell lymphoma.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg
Figure 2 Spleen
(Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg
(Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg
Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
Glyco-engineering
- Glycosylation site
- FR1 of VK
- Glycosylation Type
- N-glycosylation
- Activity
- Do not affect the immunoreactivity and can be used for conjugating therapeutic or diagnostic agents
Specifications
- Target
- CD22 (Cluster of differentiation-22)
- Host Species
- Mouse
- Type
- Mouse antibody
- Specificity
- Human
- Antibody Isotype
- IgG2a
- Clone
- LL2
- Applications
- ELISA, FC
Target
- Alternative Names
- CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
- Related Disease
- B-cell lymphoma
- Gene ID
- 933
- UniProt ID
- P20273
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD22"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody
Immunotoxin
Human Antibody
Chimeric Antibody
Humanized Antibody
Fc Glycosylation
Blocking Antibody
Rabbit Monoclonal Antibody
Fab Fragment Antibody
Recombinant Antibody
scFv Fragment Antibody
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-183-F(E) | Anti-Human CD22 Recombinant Antibody (Moxetumomab Pasudotox) | FuncS, IF, Neut, ELISA, FC, IP, ICC | Fv - disulfide stabilized |
| TAB-1714CL | Mouse Anti-CD22 Recombinant Antibody (TAB-1714CL) | ELISA, WB | Mouse IgG |
| TAB-1714CL-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1714CL-S(P)) | ELISA, WB | Mouse scFv |
| TAB-1723CL-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1723CL-S(P)) | Inhib | Mouse scFv |
| TAB-1728CL-S(P) | Anti-Human CD22 Recombinant Antibody scFv Fragment (RFB4) | IF, FC |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for Gly-001LC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FC, Cyt, Stim, PP, Agonist
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: Neut, IHC, Activ, FuncS, IF, ELISA
Application: ELISA, Inhib, FC, Neut
-1.png)
Application: ELISA, WB
Application: ELISA, IHC, IF, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
