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    Recombinant Anti-Human CXCR5 Antibody (Fc glycosylation/Low fucosylated) (CAT#: Gly-128LC-1)

    This product is a low fucosylated humanized monoclonal antibody. 40C01-VH1-Vk3 with enhanced ADCC specficfically binds to human CXCR5 and can be potentially used in the treatment of autoimmune and inflammatory disease.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Skin
    Figure 1 Skin
    (Fibroblasts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42432/123487_B_8_1.jpg
    Figure 2 Lymph node
    Figure 2 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42432/123487_A_7_8.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endocrine cells Staining: Medium Intensity: Moderate Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Enterocytes Staining: Medium Intensity: Moderate Quantity:>75% Enterocytes - Fibroblasts Staining: Low Intensity: Weak Goblet cells Staining: Medium Intensity: Moderate Quantity:>75% Mucosal lymphoid cells Staining: High Intensity: Strong Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42432/123487_A_7_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42432/123487_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42432/123487_A_8_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42432/123487_A_5_6.jpg
    RNA Expression
    Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
    Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160683-CXCR5

    Glyco-engineering

    • Glycosylation site
    • Fc region
    • Glycosylation Type
    • N-glycosylation
    • Activity
    • Enhanced ADCC

    Specifications

    • Target
    • CXCR5 (C-X-C chemokine receptor type 5)
    • Host Species
    • Human
    • Type
    • Human antibody
    • Specificity
    • Human
    • Clone
    • 40C01-VH1-Vk3
    • Applications
    • ELISA

    Target

    • Alternative Names
    • CXCR5; chemokine (C-X-C motif) receptor 5; BLR1; CD185; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemo
    • Related Disease
    • Autoimmune and inflammatory diseases

    Downloads

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    See other products for "Clone 40C01-VH1-Vk3"

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    Please select product type
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    CAT Product Name Application Type
    MOB-1702z Mouse Anti-CXCR5 Recombinant Antibody (clone 28C11) FC, ICC, IHC, Neut Mouse IgG2b
    HPAB-0109-LSX Mouse Anti-CXCR5 Recombinant Antibody (clone 2C9) ELISA, WB, Inhib Mouse IgG
    HPAB-0110-LSX Human Anti-CXCR5 Recombinant Antibody (clone H4BL2) ELISA, WB, FC, Dep Human IgG
    HPAB-0111-LSX Mouse Anti-CXCR5 Recombinant Antibody (HPAB-0111-LSX) RIA, FC, WB Mouse IgG
    HPAB-0112-LSX Human Anti-CXCR5 Recombinant Antibody (HPAB-0112-LSX) RIA, FC, WB Human IgG

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    For Research Use Only. Not For Clinical Use.

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