Recombinant Anti-Human EGFR Antibody (Fc glycosylation) (CAT#: Gly-144LC)

This product is a humanized monoclonal antibody with glycosylation site in the Fc region. The antibody with enhanced ADCC specifically binds human EGFR and can be potentially used in the treatment of metastatic colorectal cancer.

Specific Inquiry
  • Size:

  • Conjugation:

  • Endotoxin:

  • Purity:

  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Glyco-engineering

  • Glycosylation site
  • Asn297 in Fc region
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced ADCC

Specifications

  • Target
  • EGFR (Epidermal growth factor receptor)
  • Host Species
  • Human
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Antibody Isotype
  • IgG1
  • Expression Host
  • CHO
  • Applications
  • ELISA

Target

  • Alternative Names
  • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;
  • Related Disease
  • Metastatic colorectal cancer

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

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CAT Product Name Application Type
TAB-750 Anti-EGFR/HER1 Recombinant Antibody (TAB-750) Neut, ELISA, IF, IP, FuncS, FC, WB IgG1 - kappa
TAB-0225CL-F(E) Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-0225CL-F(E)) Block, Inhib, FuncS, Apop, In vivo Chimeric (Mouse/Human) Fab
PABX-051 Recombinant Human Anti-EGFR Antibody (Matuzumab) WB, Neut, FuncS, FC, ELISA, IF, Inhib IgG
PABX-051-F (E) Recombinant Mouse Anti-EGFR Antibody Fab Fragment (Matuzumab) WB, Neut, FuncS Fab
TAB-464CQ Anti-Human EGFR Recombinant Antibody (TAB-464CQ) ELISA, IHC, FC, IP, IF, FuncS IgG1, κ

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