Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
  • Home
  • EGFR
  • Recombinant Anti-Human EGFR Antibody (Fc glycosylation)

Recombinant Anti-Human EGFR Antibody (Fc glycosylation) (CAT#: Gly-144LC)

This product is a humanized monoclonal antibody with glycosylation site in the Fc region. The antibody with enhanced ADCC specifically binds human EGFR and can be potentially used in the treatment of metastatic colorectal cancer.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg
Normal Tissue
Figure 3 Colon
Figure 3 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg
Figure 7 Placenta
Figure 7 Placenta
(Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity:>75%
Decidual cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enriched (A-431)
Figure 9 RNA cell line category: Cell line enriched (A-431)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR

Glyco-engineering

  • Glycosylation site
  • Asn297 in Fc region
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced ADCC

Specifications

  • Target
  • EGFR (Epidermal growth factor receptor)
  • Host Species
  • Human
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Antibody Isotype
  • IgG1
  • Expression Host
  • CHO
  • Applications
  • ELISA

Target

  • Alternative Names
  • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;
  • Related Disease
  • Metastatic colorectal cancer

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "EGFR"

Select a product category from the dropdown menu below to view related products.
Please select product type
Chimeric Antibody Products IgG Antibody Products Fab Antibody Products Mouse Antibody Products Humanized Antibody Products Human Antibody Products Fc Glycosylation Antibody Products High-mannose Glycoform Antibody Products Deglycosylated Antibody Products Chicken IgY Antibody Products MHC Tetramer Products for Cancer Neutralizing Antibody Products Rabbit Monoclonal Antibody Products ADCC Enhanced Antibody Products Single Domain Antibody Products ScFv Antibody Products Antibody Magnetic Beads Cancer Stem Cell Biomarker Specific Antibody Products Non-Human Primate (NHP) Antibody Products
CAT Product Name Application Type
TAB-750 Anti-EGFR/HER1 Recombinant Antibody (Futuximab/Zatuximab) Neut, ELISA, IF, IP, FuncS, FC, WB IgG1 - kappa
TAB-H35 Anti-Human EGFR Recombinant Antibody (Futuximab) IF, WB, Inhib IgG1 - kappa
TAB-308MZ Human Anti-EGFR Recombinant Antibody (TAB-308MZ) FuncS Chimeric antibody (mouse/human)
TAB-272MZ-S(P) Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-272MZ-S(P)) FuncS Mouse scFv
TAB-302MZ-S(P) Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-302MZ-S(P)) ELISA Mouse scFv

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for Gly-144LC. Click the button above to contact us or submit your feedback about this product.

Popular products with customers

Figure 1 Anti-alpha 4 beta 7 Antibody (TAB-135) in ELISA

Anti-Human Integrin alpha 4 beta 7 Recombinant Antibody (Etrolizumab) (CAT# TAB-135)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 1 Anti-Human IL6R Antibody (Tocilizumab/Atlizumab) (TAB-026) in ELISA

Human Anti-Human IL6R Recombinant Antibody (TAB-026) (CAT# TAB-026)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 1 Human CD27 Recombinant Antibody (TAB-H74) in SDS-PAGE

Anti-Human CD27 Recombinant Antibody (Varlilumab) (CAT# TAB-H74)
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC

Figure 1 Human IgG1, kappa - Isotype Control Antibody (MOB-0402ZL) in SDS-PAGE

Human IgG1, kappa - Isotype Control Antibody (CAT# MOB-0402ZL)
Application: ELISA

Figure 1 Human Anti-HIV-1 Env Recombinant Antibody (PABL-151) in SDS-PAGE

Human Anti-HIV-1 Env Recombinant Antibody (clone PGDM1400) (CAT# PABL-151)
Application: Neut, FuncS

Figure 1 Recombinant Human Anti-EBV BLLF1 Antibody (PABZ-138) in SDS-PAGE

Recombinant Human Anti-EBV BLLF1 Antibody (72A1) (CAT# PABZ-138)
Application: Neut, ELISA

Figure 1 Human Anti-HIV Env Recombinant Antibody (PABL-509) in SDS-PAGE

Human Anti-HIV Env Recombinant Antibody (clone PGT121) (CAT# PABL-509)
Application: ELISA, Neut

Figure 1 Anti-Human CDCP1 Recombinant Antibody (TAB-403LC) in SDS-PAGE

Anti-Human CDCP1 Recombinant Antibody (25A11) (CAT# TAB-403LC)
Application: FC, FuncS, IHC

Figure 1 Anti-FGFR2 Antibody (TAB-055WM) in SDS-PAGE

Anti-Human FGFR2 Recombinant Antibody (GP369/4B9) (CAT# TAB-055WM)
Application: FC

Figure 1 Mouse Anti-HIV-1 p24 Recombinant Antibody (MRO-928CQ) in SDS-PAGE

Mouse Anti-HIV-1 p24 Recombinant Antibody (clone 183-H12-5C) (CAT# MRO-928CQ)
Application: ELISA

Figure 1 Mouse Anti-IFNB1 Recombinant Antibody (NEUT-987CQ) in SDS-PAGE

Mouse Anti-IFNB1 Recombinant Antibody (clone B-02) (CAT# NEUT-987CQ)
Application: Neut, ELISA

Figure 1 Anti-Human ENG Antibody (TAB-013ML) in WB

Anti-Human ENG Recombinant Antibody (Carotuximab) (CAT# TAB-013ML)
Application: ELISA, IHC, FC, IP, IF, Inhib

Figure 1 Human IgG1, lambda Isotype Control Antibody (MOB-173CQ) in SDS-PAGE

Human IgG1, lambda Isotype Control Antibody (CAT# MOB-173CQ)
Application: ELISA

Figure 1 Anti-CD40 Antibody (MOB-120CQ) in WB

Human Anti-CD40 Recombinant Antibody (clone Chi Lob 7/4) (CAT# MOB-120CQ)
Application: ELISA, IHC, IF, IP, FC, FuncS

Figure 1 Recombinant Human Anti-HCV E2 Antibody (HEPC74) (HPAB-0196CQ) in SDS-PAGE

Recombinant Human Anti-HCV E2 Antibody (HEPC74) (CAT# HPAB-0196CQ)
Application: ELISA, Neut

Figure 1 Mouse Anti-C5 Recombinant Antibody Fab Fragment (HPAB-0128CQ-F(E)) in SDS-PAGE

Mouse Anti-C5 Recombinant Antibody (clone BB5.1); Fab Fragment (CAT# HPAB-0128CQ-F(E))
Application: FC, FuncS, IA, IF, IP, IHC

Figure 1 Mouse Anti-His Tag Recombinant Antibody; Fab Fragment (HPAB-0328-WJ-F(E)) in WB

Mouse Anti-His Tag Recombinant Antibody; Fab Fragment (HPAB-0328-WJ-F(E)) (CAT# HPAB-0328-WJ-F(E))
Application: ELISA, WB

Figure 1 Mouse Anti-Citrullinated epitope Recombinant Antibody (HPAB-AP605-YC) in SDS-PAGE

Mouse Anti-Citrullinated epitope Recombinant Antibody (clone 12G1) (CAT# HPAB-AP605-YC)
Application: ELISA, IHC, WB

Figure 1 Human Anti-MS4A4A Antibody (HPAB-0904-YJ) in ELISA

Human Anti-MS4A4A Recombinant Antibody (HPAB-0904-YJ) (CAT# HPAB-0904-YJ)
Application: ELISA, FC, FuncS

Figure 1 Human Anti-Insulin Recombinant Antibody (clone mAb48) (FAMAB-0224WJ) in SDS-PAGE

Human Anti-Insulin Recombinant Antibody (clone mAb48) (CAT# FAMAB-0224WJ)
Application: ELISA, WB

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Inquiry
    Go to compare

    Go to compare