Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated) (CAT#: Gly-029LC)
This product is a human monoclonal antibody with N-glycosylation site Asn299 in the heavy chain. Antibody MORAb-003 has increased ADCC, it specifically binds human FRA and can be potentially used in the treatment of FRA-mediated disease such as cancer.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg
Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
Glyco-engineering
- Glycosylation site
- Asn299 of heavy chain
- Glycoform (ratio)
- NGA2
- Glycosylation Type
- N-glycosylation
- Activity
- Increased ADCC
Specifications
- Target
- FOLR1 (Folate receptor alpha)
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Clone
- MORAb-003
- Expression Host
- CHO-K1
- Applications
- ELISA
Target
- Alternative Names
- FOLR1; folate receptor 1 (adult); FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18;
- Related Disease
- FRA-mediated disease
- Gene ID
- 2348
- UniProt ID
- A0A024R5H1
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Recombinant Antibody
Intrabody
Humanized Antibody
Human Antibody
Mouse Antibody
Chimeric Antibody
Low- or Non-fucosylated Oligosaccharide
Fc Glycosylation
Rabbit Monoclonal Antibody
Fab Fragment Antibody
scFv Fragment Antibody
ADCC Enhanced Antibody
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1297z | Mouse Anti-FOLR1 Recombinant Antibody (clone 24A8) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2a |
| HPAB-0080-FY | Human Anti-FOLR1 Recombinant Antibody (HPAB-0080-FY) | FC | Human IgG |
| HPAB-0312-WJ | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0312-WJ) | ELISA, IHC, FC | Mouse IgG2a |
| HPAB-0313-WJ | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0313-WJ) | ELISA, IHC, FC | Mouse IgG2a |
| HPAB-0314-WJ | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0314-WJ) | ELISA, IHC, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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