Recombinant Anti-Human TNFRSF12A Antibody (Non-glycosylated)
CAT#: Gly-194LC
This product is a non-glycosylated humanized monoclonal antibody. The antibody has decreased effector function, it specifically binds to human Fn14 and can be potentially used in the treatment of cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_B_7_5.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Trophoblastic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_2_7.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (U-251 MG)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000006327-TNFRSF12A
❮
❯
Glyco-engineering
- Activity
- Decreased effector function
Specifications
- Target
- Fn14
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Antibody Isotype
- IgG4
- Clone
- P4A8_S228P/T299A
- Applications
- ELISA
Target
- Alternative Names
- TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; FN14; CD266; TWEAKR; tumor necrosis factor receptor superfamily member 12A; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor-inducible immediat
- Related Disease
- Cancer
- Gene ID
- 51330
- UniProt ID
- Q9NP84
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-221CQ | Anti-Human TNFRSF12A Recombinant Antibody (TPP-883) | ELISA, FC, WB | Human antibody |
| TAB-221CQ-S(P) | Anti-Human TNFRSF12A Recombinant Antibody scFv Fragment (TPP-883) | ELISA, FC, WB | Human antibody |
| TAB-221CQ-F(E) | Anti-Human TNFRSF12A Recombinant Antibody Fab Fragment (TPP-883) | ELISA, FC, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-222CQ | Mouse Anti-TNFRSF12A Recombinant Antibody (TAB-222CQ) | Agonist, ELISA, FuncS, WB | Mouse IgG |
| TAB-223CQ | Mouse Anti-TNFRSF12A Recombinant Antibody (TAB-223CQ) | Agonist, ELISA, FuncS | Mouse IgG |
| TAB-218CQ-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-218CQ-S(P)) | ELISA, FC, IHC | Mouse scFv |
| TAB-222CQ-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-222CQ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-223CQ-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-223CQ-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-219CQ-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-219CQ-S(P)) | ELISA, FC, IHC | Humanized scFv |
| TAB-225CQ-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-225CQ-S(P)) | ELISA, FC | Humanized scFv |
| TAB-219CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-219CQ-F(E)) | ELISA, FC, IHC | Humanized Fab |
| TAB-225CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-225CQ-F(E)) | ELISA, FC | Humanized Fab |
| TAB-227CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-227CQ-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-220CQ-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-220CQ-S(P)) | ELISA, FC, IHC | Mouse scFv |
| TAB-220CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-220CQ-F(E)) | ELISA, FC, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3610 | Rabbit Anti-TNFRSF12A Recombinant Antibody (clone DS3610AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0048-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-883); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0049-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2090); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0050-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2658); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0051-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2084); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0559-FY-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (HPAB-0559-FY-F(E)) | Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0112LY | Human Anti-TNFRSF12A Recombinant Antibody (HPAB-0112LY) | ELISA | Humanized IgG1 |
| HPAB-0113LY | Mouse Anti-TNFRSF12A Recombinant Antibody (HPAB-0113LY) | ELISA | Mouse IgG2a |
| HPAB-0114LY | Mouse Anti-TNFRSF12A Recombinant Antibody (HPAB-0114LY) | ELISA | Mouse IgG |
| HPAB-0115LY | Mouse Anti-TNFRSF12A Recombinant Antibody (HPAB-0115LY) | ELISA | Mouse IgG |
| HPAB-0116LY | Human Anti-TNFRSF12A Recombinant Antibody (HPAB-0116LY) | ELISA | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0112LY-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0112LY-S(P)) | ELISA | Humanized scfv |
| HPAB-0113LY-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0113LY-S(P)) | ELISA | Mouse scfv |
| HPAB-0114LY-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0114LY-S(P)) | ELISA | Mouse scfv |
| HPAB-0115LY-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0115LY-S(P)) | ELISA | Mouse scfv |
| HPAB-0116LY-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0116LY-S(P)) | ELISA | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY191 | Human Anti-TNFRSF12A (clone TPP-883) scFv-Fc Chimera | FC, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC657 | Recombinant Anti-TNFRSF12A Vesicular Antibody, EV Displayed (VS-0425-YC657) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7370 | Anti-TNFRSF12A Immunohistochemistry Kit | IHC | |
| VS-0525-XY7371 | Anti-Mouse TNFRSF12A Immunohistochemistry Kit | IHC |
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