Recombinant Anti-human ADAM17 Antibody scFv Fragment

Name: Recombinant Anti-human ADAM17 Antibody scFv Fragment
SKU: MOB-38-S(P)
Rating: 5 (1 reviews)

CAT#: MOB-38-S(P)

Recombinant Mouse Antibody scFv Fragment raises against Human ADAM17, expressed in E. coli.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/if_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51575/if_selected.jpg

Normal Tissue Figure 3 IHC staining of human small intestine

Immunohistochemical staining of human small intestine shows membranous and cytoplasmic positivity.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/ihc_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_B_8_5.jpg

Normal Tissue Figure 5 Colon

Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_7_3.jpg

Normal Tissue Figure 6 Liver

Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_9_4.jpg

Normal Tissue Figure 7 Kidney

Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_7_5.jpg

Normal Tissue Figure 8 Testis

Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_4_6.jpg

Normal Tissue Figure 9 Placenta

Trophoblastic cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_2_7.jpg

Normal Tissue Figure 10 Lymph node

Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_9_8.jpg

RNA Expression Figure 11 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000151694-ADAM17

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Specifications

Immunogen
Human ADAM metallopeptidase domain 17

Host Species
Mouse

Derivation
Mouse

Type
scFv

Specificity
Tested positive against native Human ADAM metallopeptidase domain 17

Species Reactivity
Human

Applications
Products can be used for: Enzyme-linked Immunosorbent Assay; Western blot; Immunoprecipitation; Functional Study

Product Property

Purity
>95% as judged by SDS-polyacrylamide gel electrophoresis

Storage
Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.

Target

Alternative Names
ADAM17; ADAM metallopeptidase domain 17; CSVP; TACE; NISBD; ADAM18; CD156B; NISBD1; disintegrin and metalloproteinase domain-containing protein 17; TNF-alpha convertase; snake venom-like protease; TNF-alpha converting enzyme; ADAM metallopeptidase domain

Gene ID
6868

UniProt ID
B2RNB2

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-38-S(P).pdf

MSDS

MSDS - MOB-38-S(P).pdf

COA

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TAB-0447CL	Anti-Human ADAM17 Recombinant Antibody (hl022C3)	ELISA, Inhib, FuncS	Human antibody
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