Recombinant Anti-human CR1 Antibody
CAT#: MOB-240
Recombinant Mouse Antibody has specificity for an antigen Human CR1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Normal Tissue
Figure 1 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_9_5.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_8_8.jpg
Normal Tissue
Figure 3 Tonsil
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_4_8.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (HL-60, HMC-1, NB-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000203710-CR1
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Specifications
- Immunogen
- Human complement component (3b/4b) receptor 1 (Knops blood group)
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native Human complement component (3b/4b) receptor 1 (Knops blood group)
- Species Reactivity
- Human
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Western blot; Immunofluorescence; Functional Study
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≤1 year at -20°C.
Target
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Customer Review
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Impressive Consistency
I've been using this antibody for my CR1 research, and the consistency in results is remarkable. It performs well across different assays, and its specificity significantly reduces background noise, making my experiments more reliable and reproducible.
Reliable Performance
As a researcher in autoimmunity, I appreciate how this antibody targets CR1 with precision. Each batch I've used is remarkably consistent, eliminating the guesswork often involved in antibody-based experiments.
High Specificity
The antibody's specificity is top-notch, crucial for detailed immunological studies involving CR1. It minimizes cross-reactivity, ensuring clean and interpretable results, which is vital for advancing my research.
Q&As
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How does this antibody relate to disease research?
A: The antibody is instrumental in studying autoimmune diseases, as CR1 is involved in immune complex clearance. It is especially relevant in researching conditions like lupus and certain types of anemia, where immune system regulation is compromised.
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Can this antibody be used in multiple species?
A: This particular antibody is human-specific. However, cross-reactivity with other species has been observed in some cases, so it's crucial to verify compatibility with non-human samples to ensure research accuracy.
-
Are there any known limitations to using this antibody?
A: While highly specific to CR1, one limitation is its human-centric design, which might require additional verification for cross-species reactivity. Furthermore, different experimental conditions might warrant optimization for best results.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "CR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-240-F(E) | Recombinant Anti-human CR1 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| MHH-240-F(E) | Recombinant Human Anti-human CR1 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
| HPAB-0421-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone E11); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0422-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0423-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9); Fab Fragment | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-240-S(P) | Recombinant Anti-human CR1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| MHH-240-S(P) | Recombinant Human Anti-human CR1 Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| HPAB-0421-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone E11); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0422-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1); scFv Fragment | ELISA, FC | Mouse scFv |
| FAMAB-0310-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone HB8592); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-496CQ | Mouse Anti-CR1 Recombinant Antibody (NEUT-496CQ) | Block, ELISA, FC, IHC-Fr, IHC-P | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0794 | Hi-Affi™ Rabbit Anti-CR1 Recombinant Antibody (clone DS794AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0310-CN | Mouse Anti-CR1 Recombinant Antibody (clone HB8592) | ELISA | Mouse IgG |
| HPAB-J0316-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0316-YC) | ELISA | Human HC IgG2 |
| HPAB-J0317-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0317-YC) | ELISA | Human HC IgG3 |
| HPAB-J0318-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0318-YC) | ELISA | Human HC IgG2 |
| HPAB-J0319-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0319-YC) | ELISA | Human HC IgG3 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY93 | Mouse Anti-NHP CR1 Recombinant Antibody (clone E11) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY535 | Anti-CR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1647 | Anti-Mouse CR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1649 | Anti-Human CR1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC567 | Recombinant Anti-CR1 Vesicular Antibody, EV Displayed (VS-0425-YC567) | ELISA, FC, Cell-uptake |
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