What applications can this anti-HSP90AB1 antibody be used for?

This Recombinant Mouse Antibody Fab Fragment is suitable for Enzyme-linked Immunosorbent Assay (ELISA), Radioimmunoassay (RIA), and Functional Studies. It has been tested positive against native Human heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1). It is Functional Grade Purified (low endotoxin, azide-free).

What is the target specificity of this antibody?

The antibody has affinity for Human HSP90AB1, which is the constitutive form of the cytosolic 90 kDa heat-shock protein. This protein is involved in signal transduction, protein folding, and degradation. The antibody specifically binds to this target and is expressed in Chinese Hamster Ovary cells (CHO).

Recombinant Anti-human HSP90AB1 Antibody Fab Fragment

CAT#: MOB-516-F(E)

Recombinant Mouse Antibody Fab Fragment molecule has affinity for the Human HSP90AB1, expressed in Chinese Hamster Ovary cells(CHO).

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55729/if_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55729/958_C6_2_blue_red_green.jpg

Subcellular Location Figure 3 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55729/911_A5_1_blue_red_green.jpg

Normal Tissue Figure 4 IHC staining of human placenta

Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/ihc_selected.jpg

Normal Tissue Figure 5 Cerebral cortex

Glial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_B_7_5.jpg

Normal Tissue Figure 6 Colon

Goblet cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_8_3.jpg

Normal Tissue Figure 7 Liver

Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_8_4.jpg

Normal Tissue Figure 8 Kidney

Cells in tubules
Staining:MediumIntensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_7_5.jpg

Normal Tissue Figure 9 Testis

Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_6_6.jpg

Normal Tissue Figure 10 Placenta

Decidual cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Trophoblastic cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_2_7.jpg

Normal Tissue Figure 11 Lymph node

Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_8_8.jpg

RNA Expression Figure 12 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000096384-HSP90AB1

❮

❯

Specifications

Immunogen
Human heat shock protein 90kDa alpha (cytosolic), class B member 1

Host Species
Mouse

Derivation
Mouse

Type
Fab

Specificity
Tested positive against native Human heat shock protein 90kDa alpha (cytosolic), class B member 1

Species Reactivity
Human

Applications
Products can be used for: Enzyme-linked Immunosorbent Assay; Radioimmunoassay; Functional Study

Product Property

Purity
90–95% (SDS-PAGE)

Storage
≤6 months at 4°C; ≥6 months at -20°C.

Target

Alternative Names
HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1; HSP84; HSPC2; HSPCB; D6S182; HSP90B; heat shock protein HSP 90-beta; HSP90-beta; heat shock 84 kDa; heat shock 90kD protein 1, beta

Gene ID
3326

UniProt ID
A0A024RD80

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for MOB-516-F(E). Click the button above to contact us or submit your feedback about this product.

Breast cancer biomarkers at key points during disease progression

Validated for Functional Studies

We needed an antibody against HSP90AB1 that was suitable for functional studies, and this recombinant Fab fragment was the perfect fit. It tested positive against the native human heat shock protein 90kDa alpha. The low endotoxin and azide-free formulation meant we could use it directly in our cell-based assays without purification steps.

Good Performance in RIA

Our lab utilized this antibody for a Radioimmunoassay (RIA) to quantify HSP90AB1 levels. The binding affinity was high, allowing for sensitive detection. Storage at -20°C has kept the reagent stable for over six months, which is great for our long-term projects involving signal transduction pathways and protein folding.

Q&As

What applications can this anti-HSP90AB1 antibody be used for?

A: This Recombinant Mouse Antibody Fab Fragment is suitable for Enzyme-linked Immunosorbent Assay (ELISA), Radioimmunoassay (RIA), and Functional Studies. It has been tested positive against native Human heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1). It is Functional Grade Purified (low endotoxin, azide-free).
What is the target specificity of this antibody?

A: The antibody has affinity for Human HSP90AB1, which is the constitutive form of the cytosolic 90 kDa heat-shock protein. This protein is involved in signal transduction, protein folding, and degradation. The antibody specifically binds to this target and is expressed in Chinese Hamster Ovary cells (CHO).

View the frequently asked questions answered by Creative Biolabs Support.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-516-F(E).pdf

MSDS

MSDS - MOB-516-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "HSP90AB1"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-516	Recombinant Anti-human HSP90AB1 Antibody	WB, ELISA, IHC, FuncS	IgG

CAT	Product Name	Application	Type
MOB-516-S(P)	Recombinant Anti-human HSP90AB1 Antibody scFv Fragment	WB, IHC, FuncS	scFv

CAT	Product Name	Application	Type
MHH-516	Recombinant Human Anti-human HSP90AB1 Antibody	ELISA, Nert, FuncS	IgG

CAT	Product Name	Application	Type
MHH-516-F(E)	Recombinant Human Anti-human HSP90AB1 Antibody Fab Fragment	ELISA, IF, FuncS	Fab

CAT	Product Name	Application	Type
MHH-516-S(P)	Recombinant Human Anti-human HSP90AB1 Antibody scFv Fragment	IF, FC, Biosensors, FuncS	scFv

CAT	Product Name	Application	Type
MOB-2426CT	Recombinant Mouse anti-Human HSP90AB1 Monoclonal antibody (31G7)	IHC-Fr, IHC-P, WB, IP, ELISA

CAT	Product Name	Application	Type
MOR-1690	Rabbit Anti-HSP90AB1 Recombinant Antibody (clone DS1690AB)	WB, IHC-P, ICC, IF, FC, IP	Rabbit IgG

CAT	Product Name	Application	Type
MHC-LC3385	PE-A2/Human HSP90AB1 (ILDKKVEKV) MHC Tetramer	FCM

CAT	Product Name	Application	Type
MHC-LC3387	PE-B*27:05/Human HSP90AB1 (RRVKEVVKK) MHC Tetramer	FCM

CAT	Product Name	Application	Type
MHC-LC3388	PE-B*27:03/Human HSP90AB1 (RRVKEVVKK) MHC Tetramer	FCM

CAT	Product Name	Application	Type
MRO-0782-CN	Rabbit Anti-HSP90AB1 Recombinant Antibody (clone CBACN-293)	WB, IF, IHC, IP, FC	Rabbit IgG

CAT	Product Name	Application	Type
MRO-0783-CN	Mouse Anti-HSP90AB1 Recombinant Antibody (clone 2-1-G3)	WB, IHC	Mouse IgG2a

CAT	Product Name	Application	Type
VS-0325-FY190	Mouse Anti-HSP90AB1 scFv-Fc Chimera (VS-0325-FY190)	WB, IP	Mouse IgG2a, scFv-Fc

CAT	Product Name	Application	Type
VS-0325-XY1070	Anti-HSP90AB1 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS13-YC555	CytoStream™ Rabbit Anti-HSP90AB1 Recombinant Antibody (VS13-YC555)	WB, IHC-P, ICC, IF, FC	Rabbit IgG

CAT	Product Name	Application	Type
VS-0525-XY3303	Anti-Mouse HSP90AB1 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY3302	Anti-Human HSP90AB1 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY3304	Anti-Chicken HSP90AB1 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY3305	Anti-Rat HSP90AB1 Immunohistochemistry Kit	IHC

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 3 Anti-Human CD20 Recombinant Antibody (TAB-016) in ELISA

Anti-Human CD20 Recombinant Antibody (Rituximab) (CAT# TAB-016)
Application: IF, IP, Neut, FuncS, ELISA, FC, WB

Figure 2 Anti-IL22 Recombinant Antibody (TAB-748) in HPLC

Anti-IL22 Recombinant Antibody (TAB-748) (CAT# TAB-748)
Application: WB, IP, IF, FuncS, FC, Neut, ELISA

Figure 9 Anti-Human BAFF Recombinant Antibody in ELISA

Anti-Human BAFF Recombinant Antibody (TAB-216) (CAT# TAB-216)
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

Figure 2 Anti-alpha 4 beta 7 Antibody (TAB-H75) in Dot Blot

Anti-Human ITGA4+ITGB7 Recombinant Antibody (TAB-H75) (CAT# TAB-H75)
Application: FC, IP, ELISA, Neut, FuncS, IF, WB

Figure 2 Anti-Human SLC34A2 Antibody (TAB-H45) in HPLC

Human Anti-SLC34A2 Recombinant Antibody (TAB-H45) (CAT# TAB-H45)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 2 Anti-Human VEGF therapeutic Antibody Fab Fragment (TAB-012-F(E)) in Dot Blot

Anti-Human VEGF Recombinant Antibody Fab Fragment (TAB-012-F(E)) (CAT# TAB-012-F(E))
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC

Figure 4 Anti-Human IAV HA Recombinant Antibody (TAB-705)-Fc silenced in ELISA

Anti-αvβ3 Integrin Recombinant Antibody (TAB-705) (CAT# TAB-705)
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC

Figure 1 Recombinant Mouse Anti-AAV 2 Antibody (MHH-19) in SDS-PAGE

Recombinant Mouse Anti-AAV 2 Antibody (CAT# MHH-19)
Application: IF, Neut, FuncS

Figure 1 Recombinant Human Anti-DENV E proteins Antibody (PABL-067) in SDS-PAGE

Recombinant Human Anti-DENV E proteins Antibody (5J7) (CAT# PABL-067)
Application: ELISA, Neut, FuncS

Figure 2 Recombinant Mouse Anti-uPAR Antibody (PABL-355) in ELISA

Mouse Anti-PLAUR Recombinant Antibody (PABL-355) (CAT# PABL-355)
Application: WB, ELISA, FuncS

Figure 2 Anti-Mouse TIGIT Recombinant Antibody (TAB-0279CL) in HPLC

Hamster Anti-TIGIT Recombinant Antibody (TAB-0279CL) (CAT# TAB-0279CL)
Application: FuncS

Figure 1 Anti-RSV F Protein Antibody (MRO-2544CQ) in ELISA

Recombinant Mouse Anti-RSV F Protein Antibody (VC62) (CAT# MRO-2544CQ)
Application: ELISA, FC, IF, WB

Figure 4 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in WB

Anti-Human C5 Recombinant Antibody (TAB-453CQ) (CAT# TAB-453CQ)
Application: ELISA, IHC, FC, IP, IF, FuncS

Figure 1 Human IgG2, kappa Isotype Control Antibody (MOB-197CQ) in SDS-PAGE

Human IgG2, kappa Isotype Control Antibody (CAT# MOB-197CQ)
Application: FC, ELISA

Figure 2 Mouse Anti-Id Recombinant Antibody (FAMAB-0073-CN) in HPLC

Mouse Anti-Id Recombinant Antibody (clone 1A7) (CAT# FAMAB-0073-CN)
Application: ELISA, FC, RIA

Figure 3 Recombinant Mouse Anti-Pfs25 Antibody (4B7) in ELISA.

Recombinant Mouse Anti-Pfs25 Antibody (4B7) (CAT# FAMAB-0226-CN)
Application: ELISA, IB, WB, IF

Figure 2 Recombinant Human Anti-EBV gH/gL Antibody (AMMO1) (PABC-311) in SEC-HPLC

Recombinant Human Anti-EBV gH/gL Antibody (AMMO1) (CAT# PABC-311)
Application: ELISA, BLI, Neut

Figure 2 Recombinant Human Anti-LAM Antibody (PABC-542) in HPLC

Recombinant Human Anti-LAM Antibody (PABC-542) (CAT# PABC-542)
Application: ELISA, WB

Figure 3 Human Anti-IL21R Recombinant Antibody (FAMAB-1203CQ) in DB

Human Anti-IL21R Recombinant Antibody (clone ATR-107) (CAT# FAMAB-1203CQ)
Application: Inhib, FC, WB

Figure 4 Mouse Anti-ACTA2 Antibody (ZG-1036F) in IHC

Mouse Anti-ACTA2 Recombinant Antibody (clone HHF35) (CAT# ZG-1036F)
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.