Recombinant Anti-human MUC17 Antibody

CAT#: MOB-681

Recombinant Mouse Antibody recognizes and reacts with Human MUC17, expressed in Chinese Hamster Ovary cells(CHO).

Gene Expression
Figure 1 IHC staining of human small intestine Figure 2 IHC staining of human liver Figure 3 Colon

Specifications

  • Immunogen
  • Human mucin 17, cell surface associated
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native Human mucin 17, cell surface associated
  • Species Reactivity
  • Human
  • Applications
  • Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Western blot; Immunoprecipitation; Functional Study

Product Property

  • Purity
  • Purity>95% by SDS-PAGE
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • MUC17; mucin 17, cell surface associated; MUC3; mucin-17; MUC-3; MUC-17; membrane mucin MUC17; secreted mucin MUC17; small intestinal mucin-3; small intestinal mucin MUC3
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Breast cancer biomarkers at key points during disease progression
Effective Mucin 17 Detection
This recombinant antibody was highly effective in detecting human MUC17 in our ELISA and Western blot experiments. It specifically recognized the cell surface-associated mucin, which helped us study its function in epithelial cells. The antibody was purified to a functional grade, making it suitable for our sensitive immunoprecipitation protocols.
Breast cancer biomarkers at key points during disease progression
Good For Functional Studies
We used this mouse antibody for functional studies investigating the cytoprotection properties of membrane mucins. It performed well and showed greater than 95% purity on SDS-PAGE. We stored aliquots at -20°C as instructed, and the antibody maintained its reactivity against the native human mucin 17 target throughout our project.

Q&As

  1. What research applications is this MUC17 antibody useful for?

    A: This recombinant antibody can be useful in a variety of applications, including Enzyme-linked Immunosorbent Assay (ELISA), Western blot, Immunoprecipitation, and Functional Studies. It specifically recognizes Human mucin 17, a cell surface-associated membrane mucin.

  2. Where is the target protein MUC17 typically located?

    A: MUC17 is a membrane mucin found on the cell surface. It functions in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties, particularly in cancer cells that lose polarization.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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