Recombinant Human Anti-human ADAMTS5 Antibody
CAT#: MHH-39
Recombinant Human Antibody coresponds to Human ADAMTS5, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ADAMTS5 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ADAMTS5 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30906/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human caudate
Immunohistochemical staining of human caudate shows strong cytoplasmic positivity in glial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5661/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human fallopian tube
Immunohistochemical staining of human fallopian tube shows strong positivity in cytoplasm and cilia of glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/ihc_selected.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, RH-30, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154736-ADAMTS5
❮
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Specifications
- Immunogen
- Human ADAM metallopeptidase with thrombospondin type 1 motif, 5
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human ADAM metallopeptidase with thrombospondin type 1 motif, 5
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Enzyme-linked Immunosorbent Assay; Western blot; Flow Cytometry; Functional Study
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- ADAMTS5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11; ADAM-TS 11; A disintegrin and metalloproteinase with thrombospondin motifs 5; aggrecanase-2; a disintegrin and metalloproteinas
- Gene ID
- 11096
- UniProt ID
- Q9UNA0
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-39 | Recombinant Anti-human ADAMTS5 Antibody | ELISA, WB, Dot, FuncS | IgG |
| PABL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4) | Inhib, WB, ELISA, FuncS | Mouse IgG1 |
| PABL-391 | Mouse Anti-ADAMTS5 Recombinant Antibody (PABL-391) | WB, ELISA, FuncS | Mouse IgG2c |
| MOB-142CQ | Mouse Anti-ADAMTS5 Recombinant Antibody (clone CBLS-195) | ELISA, WB, IP | Mouse IgG2b |
| HPAB-AP227-YC | Mouse Anti-ADAMTS5 Recombinant Antibody (HPAB-AP227-YC) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-39-F(E) | Recombinant Anti-human ADAMTS5 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| MHH-39-F(E) | Recombinant Human Anti-human ADAMTS5 Antibody Fab Fragment | IF, FC, FuncS | Fab |
| PFBL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| PFBL-391 | Mouse Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (PFBL-391) | WB, ELISA, FuncS | Mouse Fab |
| HPAB-AP227-YC-F(E) | Mouse Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (HPAB-AP227-YC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0684CLV | Anti-Human ADAMTS5 Recombinant Antibody (12F4.1H7) | FuncS | |
| TAB-0685CLV | Anti-Human ADAMTS5 Recombinant Antibody (7B4.1E11) | FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0692CLV | Anti-Human ADAMTS5 Recombinant Antibody (7B4) | ICC, ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0693CLV | Humanized Anti-Human ADAMTS5 Recombinant Antibody (12F4.1H7) | FuncS | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP227-YC-S(P) | Mouse Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP227-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP228-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP228-YC-S(P)) | ELISA | Human scFv |
| HPAB-AP229-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP229-YC-S(P)) | ELISA | Human scFv |
| HPAB-AP230-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP230-YC-S(P)) | ELISA | Human scFv |
| HPAB-AP231-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP231-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC23 | CytoStream™ Rabbit Anti-ADAMTS5 Recombinant Antibody (VS13-YC23) | WB, ICC, IF, FC | Rabbit IgG |
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