Recombinant Human Anti-human CCR2 Antibody
CAT#: MHH-159
Recombinant Human Antibody prepared by a genetic engineering technique which specifically reacts with Human CCR2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CCR2 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CCR2 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/63255/1926_C6_4_selected.jpg
Normal Tissue
Figure 2 IHC staining of human cervix, uterine
Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/ihc_selected.jpg
Normal Tissue
Figure 3 Cervix
Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_B_8_3.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (Karpas-707, THP-1, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000121807-CCR2
❮
❯
Specifications
- Immunogen
- Human chemokine (C-C motif) receptor 2
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human chemokine (C-C motif) receptor 2
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Western blot; Immunoprecipitation; Functional Study
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- CCR2; chemokine (C-C motif) receptor 2; CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; C-C chemokine receptor type 2; MCP-1 receptor; monocyte chemotactic protein 1 receptor; monocyte chemoattractant protein 1 receptor
- Gene ID
- 729230
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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