Recombinant Human Anti-human CCR6 Antibody (CAT#: MHH-160)
Recombinant Human Antibody reacts with an antigen Human CCR6, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CCR6 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CCR6 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_B_8_5.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_B_8_5.jpg
Figure 2 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_9_3.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_9_3.jpg
Figure 3 Liver
(Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_8_4.jpg
(Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_8_4.jpg
Figure 4 Kidney
(Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_8_5.jpg
(Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_8_5.jpg
Figure 5 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_9_8.jpg
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_9_8.jpg
Figure 6 RNA cell line category: Group enriched (Hep G2, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112486-CCR6
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112486-CCR6
Specifications
- Immunogen
- Human chemokine (C-C motif) receptor 6
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human chemokine (C-C motif) receptor 6
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Western blot; Radioimmunoassay; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- CCR6; chemokine (C-C motif) receptor 6; BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6; C-C chemokine receptor type 6; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupl
- Gene ID
- 1235
- UniProt ID
- P51684
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-160 | Recombinant Anti-human CCR6 Antibody | WB, FC, FuncS | IgG |
| HPAB-0083-CN | Human Anti-CCR6 Recombinant Antibody (HPAB-0083-CN) | Neut, ELISA, FC | Chimeric (mouse/human) IgG1 |
| HPAB-AP022-YC | Human Anti-CCR6 Recombinant Antibody (clone R601) | FC, IF | Human IgG1 |
| HPAB-AP026-YC | Human Anti-CCR6 Recombinant Antibody (clone R619) | FC, IF | Human IgG1 |
| VS-0723-WK94 | Human Anti-CCR6 Recombinant Antibody (VS-0723-WK94) | FC | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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