Recombinant Human Anti-human CCR7 Antibody (CAT#: MHH-161)
Recombinant Human Antibody specifically binds to Human CCR7, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CCR7 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CCR7 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31383/1522_F9_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31383/1522_F9_3_selected.jpg
Figure 2 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74467/1566_C10_2_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74467/1566_C10_2_selected.jpg
Figure 3 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_3.jpg
Figure 4 Lymph node
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_8.jpg
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126353-CCR7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126353-CCR7
Specifications
- Immunogen
- Human chemokine (C-C motif) receptor 7
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human chemokine (C-C motif) receptor 7
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Western blot; Immunoprecipitation; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4°C, -20°C if preferred
Target
- Alternative Names
- CCR7; chemokine (C-C motif) receptor 7; BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7; C-C chemokine receptor type 7; MIP-3 beta receptor; CC chemokine receptor 7; Bukitts lymphoma receptor 2; Epstein-Barr virus induced gene 1; EBV-induced G protein-
- Gene ID
- 1236
- UniProt ID
- P32248
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-161 | Recombinant Anti-human CCR7 Antibody | WB, Dot, FuncS | IgG |
| MOB-0375CT | Mouse Anti-CCR7 Recombinant Antibody (clone NN0078-0M22) | FC, IHC-P | Mouse IgG2 |
| HPAB-0473-CN | Mouse Anti-CCR7 Recombinant Antibody (HPAB-0473-CN) | ELISA, FC, Block | Mouse IgG |
| MRO-0265-CN | Rabbit Anti-CCR7 Recombinant Antibody (clone CBACN-102) | WB, IF, IHC, IP | Rabbit IgG |
| VS11-QX22 | Mouse Anti-CCR7 Recombinant Antibody (clone 4B12) | FC, IP, FuncS | Mouse IgG2b, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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